Datasets:

IPA-Marketing
/

Dry-Granulation_Roll-Compaction_and_Milling

run_id int64 1 720	material stringclasses 3 values	deformation_type stringclasses 3 values	true_density_gcc float64 1.49 1.55	compactor_config stringclasses 3 values	roll_diameter_mm int64 120 250	roll_width_mm int64 25 30	sealing_system stringclasses 2 values	roll_surface stringclasses 2 values	scf_kN_per_cm float64 2.02 20	gap_width_mm float64 1.01 6	roll_speed_rpm float64 1.1 30	feed_screw_rpm float64 10 120	densification_factor float64 1.81 3.84	nip_angle_deg float64 9.82 18.4	peak_pressure_MPa float64 6.1 175	ribbon_rel_density float64 0.42 0.95	ribbon_density_gcc float64 0.63 1.47	ribbon_porosity float64 0.05 0.58	density_CV_percent float64 1.22 15	in_zinchuk_window stringclasses 2 values	fines_fraction_pct float64 3 50.4	granule_d50_um float64 50 589	throughput_kg_hr float64 2.38 261
1	MCC_Mannitol_Mix	mixed	1.52	Small_D120	120	25	side_sealing	knurled	10.41	2.85	11.29	97	2.167	15.93	62.4	0.769	1.1689	0.231	5.79	Yes	21.52	337	49.09
2	MCC_Mannitol_Mix	mixed	1.52	Medium_D250_W30	250	30	side_sealing	knurled	15.55	3.58	24.95	59.3	2.505	15.32	46.5	0.6836	1.0391	0.3164	6.7	Yes	24.44	235	142.82
3	MCC_101	plastic	1.55	Medium_D250	250	25	rim_rolls	smooth	10.06	2.83	6.67	75.4	2.693	11.39	40.5	0.7504	1.1631	0.2496	3.14	Yes	13.84	408.3	29.19
4	Mannitol_SD	brittle	1.49	Medium_D250_W30	250	30	rim_rolls	knurled	9.79	5.5	10.26	86.6	2.213	15.67	28.6	0.5887	0.8771	0.4113	2.77	No	29.02	134.8	77.93
5	Mannitol_SD	brittle	1.49	Medium_D250	250	25	rim_rolls	smooth	15.16	3.74	19.02	50.9	2.471	10.11	68.8	0.7321	1.0909	0.2679	5.32	Yes	23.33	236.1	100.51
6	MCC_Mannitol_Mix	mixed	1.52	Medium_D250	250	25	rim_rolls	smooth	16.29	3.6	10.47	65	2.501	10.72	69.6	0.8328	1.2658	0.1672	3.59	No	11.26	370.2	59.33
7	MCC_Mannitol_Mix	mixed	1.52	Medium_D250_W30	250	30	rim_rolls	smooth	12.21	3.08	23.45	115.4	2.621	10.6	52.8	0.7185	1.0921	0.2815	3.23	Yes	18.69	334.2	119.93
8	MCC_101	plastic	1.55	Small_D120	120	25	rim_rolls	smooth	14.09	3.44	3.69	11.4	2.064	10.65	126.3	0.95	1.4725	0.05	4.08	No	5.11	551.7	24.39
9	MCC_101	plastic	1.55	Medium_D250_W30	250	30	side_sealing	knurled	13.5	4.3	16.84	110.9	2.373	16.01	38.7	0.6655	1.0316	0.3345	5.1	Yes	23.7	289.2	117.26
10	MCC_101	plastic	1.55	Medium_D250	250	25	side_sealing	knurled	3.22	4.03	25.86	79.1	2.417	15.65	9.4	0.4696	0.728	0.5304	6.47	No	40.81	116.5	96.75
11	Mannitol_SD	brittle	1.49	Small_D120	120	25	side_sealing	smooth	3.51	3.77	7.72	66.8	2.015	10.68	31.4	0.5664	0.8439	0.4336	6.41	No	39.95	115.1	32.49
12	MCC_101	plastic	1.55	Small_D120	120	25	side_sealing	knurled	16.75	3.37	17.19	115.4	2.075	16.02	99.9	0.8643	1.3397	0.1357	6.67	No	14.77	485.2	98.39
13	MCC_Mannitol_Mix	mixed	1.52	Medium_D250_W30	250	30	rim_rolls	knurled	8.19	4.44	18.53	55	2.35	15.39	24.4	0.6137	0.9328	0.3863	4.08	Yes	29.96	179.1	113.82
14	Mannitol_SD	brittle	1.49	Medium_D250	250	25	rim_rolls	smooth	6.81	5.57	10.24	74.4	2.206	10.57	29.5	0.5957	0.8875	0.4043	3.95	No	29.8	165.8	62.96
15	MCC_101	plastic	1.55	Small_D120	120	25	rim_rolls	knurled	11.98	3.19	7.98	96	2.104	16.43	69.6	0.8402	1.3023	0.1598	2.64	No	12.27	459.3	46.65
16	MCC_Mannitol_Mix	mixed	1.52	Medium_D250	250	25	side_sealing	smooth	8.03	3.84	28.78	113	2.453	10.5	35.1	0.5955	0.9052	0.4045	7.98	No	33.18	183.1	126.45
17	Mannitol_SD	brittle	1.49	Medium_D250_W30	250	30	side_sealing	knurled	17.31	5.9	8.99	79.1	2.172	15.7	50.5	0.6926	1.0319	0.3074	6.17	Yes	30.31	267.8	82.61
18	MCC_Mannitol_Mix	mixed	1.52	Medium_D250	250	25	side_sealing	smooth	12.39	4.21	15.46	109.6	2.387	10.8	52.6	0.7234	1.0996	0.2766	6.53	Yes	27.06	311.7	91.42
19	MCC_101	plastic	1.55	Small_D120	120	25	rim_rolls	knurled	15.89	4.85	3.27	33.3	1.895	16.3	93.1	0.9393	1.4559	0.0607	2.39	No	5.28	536.5	30.09
20	MCC_Mannitol_Mix	mixed	1.52	Small_D120	120	25	side_sealing	smooth	6.87	5.6	18.05	29.5	1.834	10.23	64.2	0.7517	1.1425	0.2483	8.02	Yes	23.31	303.4	147.7
21	Mannitol_SD	brittle	1.49	Small_D120	120	25	rim_rolls	knurled	19.56	3.76	26.72	11.7	2.016	14.81	126.1	0.8591	1.2801	0.1409	3.81	No	10.95	311.3	161.91
22	Mannitol_SD	brittle	1.49	Small_D120	120	25	rim_rolls	knurled	8.58	3.18	23.53	114.1	2.106	15.34	53.4	0.6725	1.002	0.3275	2.75	Yes	24.86	190.6	97.91
23	MCC_101	plastic	1.55	Small_D120	120	25	rim_rolls	smooth	6.23	5.96	5.7	22.1	1.808	10.74	55.4	0.8225	1.2749	0.1775	5.36	No	16.92	458.6	56.25
24	Mannitol_SD	brittle	1.49	Medium_D250_W30	250	30	side_sealing	knurled	19.76	3.53	13.75	96.4	2.515	15.55	58.3	0.7071	1.0535	0.2929	6.39	Yes	27.96	236.4	78.24
25	MCC_101	plastic	1.55	Medium_D250	250	25	side_sealing	smooth	18.88	6	22.38	57.4	2.162	10.59	81.7	0.7689	1.1919	0.2311	7.58	Yes	16.53	312.2	204.96
26	Mannitol_SD	brittle	1.49	Medium_D250_W30	250	30	rim_rolls	smooth	4.09	4.49	26.75	106.8	2.344	10.25	18.3	0.5132	0.7647	0.4868	5.04	No	34.13	91.7	140.25
27	Mannitol_SD	brittle	1.49	Medium_D250	250	25	side_sealing	knurled	9.75	4.73	15.41	22.3	2.308	14.95	29.9	0.5719	0.8522	0.4281	7.06	No	33.46	190.7	80.72
28	MCC_Mannitol_Mix	mixed	1.52	Small_D120	120	25	rim_rolls	knurled	5.41	2.6	17.43	53.1	2.223	15.4	33.6	0.632	0.9606	0.368	3.89	Yes	23.92	243.1	55.33
29	Mannitol_SD	brittle	1.49	Medium_D250_W30	250	30	rim_rolls	knurled	5.48	3	16.25	20.7	2.644	14.93	16.8	0.4996	0.7444	0.5004	4.51	No	38.83	81.6	57.99
30	MCC_Mannitol_Mix	mixed	1.52	Medium_D250	250	25	side_sealing	knurled	7.67	3.37	26.9	99.8	2.55	15.47	22.7	0.5385	0.8185	0.4615	6.49	No	36.29	108.7	93.23
31	MCC_Mannitol_Mix	mixed	1.52	Medium_D250	250	25	rim_rolls	knurled	10.38	5.8	28.16	109	2.181	15.49	30.7	0.5914	0.899	0.4086	3.33	No	27.25	139.7	187.08
32	MCC_Mannitol_Mix	mixed	1.52	Medium_D250	250	25	rim_rolls	smooth	4.89	4.92	5.34	90.1	2.284	11.48	19.5	0.5655	0.8596	0.4345	3.85	No	30.59	177.4	27.78
33	Mannitol_SD	brittle	1.49	Medium_D250	250	25	side_sealing	smooth	11.28	4.29	5.84	95.5	2.374	11.2	46.2	0.6483	0.9659	0.3517	7.39	Yes	31.43	154.4	32.37
34	MCC_101	plastic	1.55	Medium_D250_W30	250	30	side_sealing	smooth	8.73	1.47	25.22	63.5	3.349	10.59	37.8	0.6411	0.9936	0.3589	7.67	Yes	28.21	225.7	59.28
35	MCC_Mannitol_Mix	mixed	1.52	Medium_D250	250	25	side_sealing	smooth	11.46	3.37	2.41	57.8	2.551	11.84	44.4	0.7255	1.1027	0.2745	7.65	Yes	23.13	304.6	10.74
36	Mannitol_SD	brittle	1.49	Medium_D250_W30	250	30	side_sealing	smooth	12.78	2.9	19.52	85	2.671	10.29	56.9	0.6942	1.0344	0.3058	7.65	Yes	31.71	196.1	86.19
37	Mannitol_SD	brittle	1.49	Small_D120	120	25	rim_rolls	smooth	2.61	1.27	20.22	44.8	2.747	10.05	24.8	0.5607	0.8354	0.4393	5.26	No	27.63	71.9	29.62
38	MCC_101	plastic	1.55	Medium_D250_W30	250	30	side_sealing	knurled	9.1	1.13	23.07	71.9	3.679	15.66	26.6	0.597	0.9253	0.403	6.08	No	30.61	234.9	39.33
39	MCC_101	plastic	1.55	Medium_D250_W30	250	30	rim_rolls	smooth	6.18	2.66	2.72	112.5	2.747	12.71	22.3	0.6564	1.0174	0.3436	9.54	Yes	21.12	339.9	10.52
40	Mannitol_SD	brittle	1.49	Small_D120	120	25	side_sealing	smooth	16.14	2.51	12.94	55.1	2.245	10.28	149.9	0.8873	1.3221	0.1127	7.95	No	19.32	371.4	55.44
41	MCC_Mannitol_Mix	mixed	1.52	Small_D120	120	25	side_sealing	knurled	5.95	4.04	18.44	116	1.98	15.73	36.1	0.6453	0.9809	0.3547	5.61	Yes	30.24	259	93.15
42	Mannitol_SD	brittle	1.49	Medium_D250_W30	250	30	rim_rolls	knurled	6.01	1.48	25.43	72.7	3.343	15.13	18.2	0.5341	0.7959	0.4659	3.58	No	30.63	85.8	44.75
43	MCC_101	plastic	1.55	Medium_D250_W30	250	30	rim_rolls	smooth	9.12	3.02	20.46	31.4	2.638	10.46	39.9	0.6888	1.0677	0.3112	5.33	Yes	16.66	281.2	100.66
44	MCC_Mannitol_Mix	mixed	1.52	Small_D120	120	25	side_sealing	knurled	6.15	3	6.15	63.3	2.139	16.06	36.6	0.6731	1.0231	0.3269	6.07	Yes	28.2	218.3	21.99
45	MCC_101	plastic	1.55	Small_D120	120	25	side_sealing	knurled	11.56	4.79	21.26	100.8	1.901	15.83	69.7	0.7594	1.1771	0.2406	6.56	Yes	18.72	325.6	153.64
46	Mannitol_SD	brittle	1.49	Medium_D250_W30	250	30	rim_rolls	smooth	18.09	2.53	2.66	41.9	2.789	11.17	74.3	0.7776	1.1586	0.2224	4.61	Yes	17.46	294	12.68
47	MCC_101	plastic	1.55	Medium_D250	250	25	side_sealing	knurled	5.88	3.72	29.64	64.5	2.476	15.55	17.3	0.4915	0.7619	0.5085	7.13	No	39.65	172.9	108.17
48	Mannitol_SD	brittle	1.49	Medium_D250_W30	250	30	side_sealing	knurled	8.35	4.38	28.39	117.6	2.36	15.27	25.1	0.545	0.812	0.455	6.91	No	38.53	165.1	155.23
49	MCC_101	plastic	1.55	Medium_D250_W30	250	30	side_sealing	smooth	11.72	1.56	22.01	75.5	3.28	10.69	50.3	0.7215	1.1184	0.2785	7.84	Yes	22.16	361.5	58.99
50	MCC_101	plastic	1.55	Medium_D250	250	25	side_sealing	smooth	8.25	3.55	25.91	107	2.511	10.77	35.1	0.6388	0.9902	0.3612	7.69	Yes	24.21	264.4	114.35
51	MCC_101	plastic	1.55	Medium_D250	250	25	side_sealing	smooth	11.05	3.58	26.93	49.1	2.505	10.5	48.2	0.6577	1.0194	0.3423	7.16	Yes	28.57	302.9	125.5
52	MCC_101	plastic	1.55	Medium_D250_W30	250	30	side_sealing	knurled	14.89	5.77	19.37	74.6	2.184	15.74	43.4	0.691	1.0711	0.309	5.76	Yes	23.49	282.8	184.03
53	Mannitol_SD	brittle	1.49	Medium_D250_W30	250	30	side_sealing	knurled	2.51	1.82	18.92	54.8	3.112	15.13	7.6	0.4233	0.6307	0.5767	6.72	No	50.35	84.2	35.07
54	MCC_Mannitol_Mix	mixed	1.52	Medium_D250	250	25	side_sealing	knurled	5.77	1.81	5.21	95.2	3.114	16.56	16	0.5641	0.8575	0.4359	6.73	No	31.8	183.9	10.27
55	Mannitol_SD	brittle	1.49	Medium_D250	250	25	rim_rolls	smooth	16.61	3.55	27.29	36.2	2.511	9.94	76.6	0.7499	1.1173	0.2501	4.87	Yes	20.85	199.4	139.22
56	Mannitol_SD	brittle	1.49	Medium_D250_W30	250	30	rim_rolls	knurled	12.96	3.27	24.09	41.3	2.574	14.99	39.6	0.6155	0.917	0.3845	4.3	Yes	30.48	138.2	112.59
57	MCC_101	plastic	1.55	Small_D120	120	25	rim_rolls	knurled	19.36	2.76	8.93	74.2	2.187	16.16	114.4	0.9491	1.4711	0.0509	3.71	No	5.62	538.1	44.25
58	MCC_101	plastic	1.55	Medium_D250_W30	250	30	rim_rolls	smooth	8.14	5.05	12.61	35.1	2.266	10.62	35.1	0.7042	1.0916	0.2958	3.79	Yes	20.22	343.4	106.12
59	MCC_Mannitol_Mix	mixed	1.52	Medium_D250_W30	250	30	side_sealing	smooth	16.81	5.64	15.57	60	2.199	10.49	73.5	0.793	1.2054	0.207	7.8	Yes	21.16	344	163.98
60	MCC_101	plastic	1.55	Medium_D250_W30	250	30	rim_rolls	knurled	14.27	3.66	9.75	119	2.487	16.45	39.8	0.7458	1.156	0.2542	2.42	Yes	16.85	341.1	62.93
61	MCC_Mannitol_Mix	mixed	1.52	Medium_D250_W30	250	30	rim_rolls	knurled	15.98	3.86	12.43	11	2.449	15.13	48.4	0.718	1.0913	0.282	3.64	Yes	19.95	227.2	80.4
62	Mannitol_SD	brittle	1.49	Medium_D250	250	25	rim_rolls	knurled	16.34	5.24	13.76	76.8	2.243	15.42	48.6	0.6786	1.0111	0.3214	2.85	Yes	22.86	227.7	94.61
63	MCC_101	plastic	1.55	Medium_D250_W30	250	30	side_sealing	knurled	15.76	3.68	22.01	88	2.483	15.75	45.8	0.698	1.0819	0.302	6.34	Yes	26.94	262.7	133.45
64	MCC_101	plastic	1.55	Small_D120	120	25	rim_rolls	smooth	12.4	3.59	12.08	18.6	2.041	10.46	113.2	0.9382	1.4542	0.0618	4.63	No	5.77	520.2	80.66
65	MCC_Mannitol_Mix	mixed	1.52	Medium_D250_W30	250	30	side_sealing	knurled	14.7	1.49	26.06	81.5	3.334	15.41	43.7	0.6815	1.0359	0.3185	5.51	Yes	27.29	218.7	62.29
66	Mannitol_SD	brittle	1.49	Medium_D250_W30	250	30	side_sealing	knurled	11.49	3.61	19.56	78.7	2.497	15.26	34.5	0.5951	0.8867	0.4049	6.25	No	33.81	155	95.21
67	Mannitol_SD	brittle	1.49	Medium_D250_W30	250	30	rim_rolls	smooth	16.59	2.86	21.99	19.8	2.684	9.88	77	0.7829	1.1666	0.2171	4.65	Yes	17.08	266.2	112.42
68	Mannitol_SD	brittle	1.49	Medium_D250_W30	250	30	rim_rolls	knurled	4.89	5.27	7.7	18.1	2.24	15.07	14.9	0.4907	0.7312	0.5093	3.41	No	40.11	83.9	45.3
69	MCC_101	plastic	1.55	Medium_D250_W30	250	30	side_sealing	knurled	11.67	4.16	28.65	66.6	2.395	15.56	34.4	0.5802	0.8994	0.4198	6.45	No	32.92	222.4	164.59
70	MCC_101	plastic	1.55	Medium_D250_W30	250	30	rim_rolls	knurled	10.76	2.36	17.34	91.2	2.852	15.88	31	0.6784	1.0516	0.3216	3.36	Yes	24.31	300.3	64.45
71	Mannitol_SD	brittle	1.49	Medium_D250_W30	250	30	rim_rolls	knurled	7.19	4.97	24.92	117.8	2.277	15.33	21.5	0.5263	0.7842	0.4737	3.31	No	32.95	115	150.2
72	Mannitol_SD	brittle	1.49	Small_D120	120	25	rim_rolls	knurled	15.37	2.93	24.05	37.1	2.152	14.97	98.1	0.8237	1.2273	0.1763	3.78	No	15.5	329.5	109.92
73	MCC_101	plastic	1.55	Small_D120	120	25	rim_rolls	smooth	15.33	5.23	27.16	119.2	1.862	10.8	135.6	0.8402	1.3023	0.1598	3.52	No	9.57	406.6	235.65
74	MCC_Mannitol_Mix	mixed	1.52	Medium_D250_W30	250	30	rim_rolls	knurled	6.68	5.7	7.86	90.1	2.192	16.15	19	0.5718	0.8692	0.4282	2.22	No	26.19	215.2	60.42
75	Mannitol_SD	brittle	1.49	Medium_D250	250	25	rim_rolls	knurled	7.8	5.76	14.1	54	2.186	15.24	23.5	0.5504	0.8201	0.4496	3.31	No	31.93	141.6	84.95
76	MCC_Mannitol_Mix	mixed	1.52	Medium_D250	250	25	rim_rolls	knurled	12.57	3.3	2.85	31.2	2.567	16.11	35.8	0.7026	1.0679	0.2974	2.11	Yes	23.44	303.9	9.92
77	MCC_101	plastic	1.55	Small_D120	120	25	rim_rolls	knurled	19.48	3.15	9.75	51	2.111	15.88	117.1	0.9271	1.437	0.0729	3.17	No	3	533.2	56.14
78	MCC_101	plastic	1.55	Medium_D250	250	25	rim_rolls	knurled	4.05	3.88	22.66	24	2.444	15.4	12.1	0.507	0.7858	0.493	3.89	No	30.22	124.3	88.58
79	MCC_Mannitol_Mix	mixed	1.52	Medium_D250	250	25	side_sealing	knurled	3.66	3.9	15.93	11.6	2.442	15.11	11.1	0.4934	0.75	0.5066	7.69	No	41.34	129.1	61.22
80	MCC_Mannitol_Mix	mixed	1.52	Medium_D250_W30	250	30	side_sealing	knurled	5.82	2.14	13.43	50.2	2.944	15.48	17.2	0.5714	0.8685	0.4286	6.26	No	31.72	163	38.15
81	Mannitol_SD	brittle	1.49	Medium_D250_W30	250	30	rim_rolls	knurled	16.33	5.96	20.93	81.7	2.166	15.24	49.1	0.6693	0.9973	0.3307	3.44	Yes	27.31	207.9	192.73
82	MCC_101	plastic	1.55	Small_D120	120	25	side_sealing	knurled	3.47	5.55	11.28	119.1	1.837	16.33	20.3	0.5935	0.9199	0.4065	5.89	No	28.66	244.6	74.4
83	Mannitol_SD	brittle	1.49	Small_D120	120	25	rim_rolls	smooth	17.46	3.96	23.8	50.3	1.991	10.04	166.1	0.8893	1.3251	0.1107	4.76	No	11.48	404.4	160.85
84	MCC_101	plastic	1.55	Small_D120	120	25	rim_rolls	smooth	12.21	3.21	9.92	87.3	2.101	11.2	104.1	0.9096	1.4099	0.0904	3.52	No	9.41	510.9	59.28
85	MCC_101	plastic	1.55	Medium_D250_W30	250	30	rim_rolls	smooth	8.37	4.22	28.93	85.7	2.385	10.64	36	0.6256	0.9697	0.3744	4.23	Yes	26.06	186.9	180.47
86	MCC_Mannitol_Mix	mixed	1.52	Medium_D250_W30	250	30	side_sealing	smooth	10.26	1.7	9.85	70	3.181	10.81	43.5	0.7107	1.0803	0.2893	7.05	Yes	21.38	329.6	31.39
87	Mannitol_SD	brittle	1.49	Small_D120	120	25	side_sealing	knurled	10.18	1.2	2.4	118	2.799	17.42	55.8	0.681	1.0147	0.319	12.27	Yes	29.16	239.1	3.72
88	MCC_101	plastic	1.55	Small_D120	120	25	rim_rolls	knurled	16.73	1.1	16.96	48.6	2.883	15.63	102.2	0.8844	1.3708	0.1156	3.38	No	7.01	467.6	31.88
89	MCC_101	plastic	1.55	Medium_D250	250	25	rim_rolls	knurled	4.17	2.29	24.17	25	2.883	15.4	12.4	0.4966	0.7698	0.5034	4.34	No	31.31	154.2	55.38
90	MCC_Mannitol_Mix	mixed	1.52	Medium_D250_W30	250	30	side_sealing	knurled	4.55	4.05	24.7	35.5	2.414	15.2	13.7	0.4934	0.75	0.5066	7.57	No	37.9	134.6	116.03
91	MCC_101	plastic	1.55	Medium_D250	250	25	side_sealing	knurled	4.78	5.83	5.51	100.7	2.179	16.81	13	0.5587	0.866	0.4413	7.23	No	35.32	222.1	35.39
92	MCC_101	plastic	1.55	Medium_D250	250	25	side_sealing	knurled	13.09	1.06	21.05	114.4	3.767	15.9	37.7	0.6879	1.0662	0.3121	5.3	Yes	22.4	285.7	33.52
93	MCC_101	plastic	1.55	Small_D120	120	25	side_sealing	knurled	2.51	5.95	21.33	39.6	1.808	15.51	15.5	0.5199	0.8059	0.4801	7.11	No	36.16	106.7	130.97
94	MCC_Mannitol_Mix	mixed	1.52	Small_D120	120	25	rim_rolls	smooth	13.85	2.43	27.96	72.8	2.266	10.35	127.8	0.8672	1.3182	0.1328	4.47	No	10.99	420.4	113.25
95	MCC_Mannitol_Mix	mixed	1.52	Small_D120	120	25	rim_rolls	knurled	18.1	1.27	11.19	108.2	2.747	16.01	107.9	0.8882	1.35	0.1118	2.1	No	10.78	424.7	22.74
96	MCC_Mannitol_Mix	mixed	1.52	Small_D120	120	25	side_sealing	smooth	17.03	5.17	21.27	98.9	1.867	10.57	153.8	0.8958	1.3616	0.1042	6.58	No	12.52	456.4	192.09
97	Mannitol_SD	brittle	1.49	Medium_D250	250	25	rim_rolls	smooth	17.14	1.95	24.69	49.1	3.039	10.02	78.4	0.7654	1.1405	0.2346	4.27	Yes	19.47	289.8	69.46
98	Mannitol_SD	brittle	1.49	Medium_D250_W30	250	30	rim_rolls	smooth	11.88	1.28	2.71	76.2	3.515	11.75	46.3	0.6725	1.0021	0.3275	5.96	Yes	26.15	241.7	6.72
99	MCC_101	plastic	1.55	Medium_D250	250	25	rim_rolls	smooth	7.26	1.87	10.12	100.4	3.079	11.28	29.5	0.7086	1.0983	0.2914	3.42	Yes	19.81	319.7	26.84
100	MCC_101	plastic	1.55	Medium_D250	250	25	side_sealing	knurled	15.72	4.21	11.43	25	2.388	15.55	46.4	0.7623	1.1816	0.2377	6.56	Yes	20.38	373.7	70.04

End of preview. Expand in Data Studio

Dry Granulation: Multi-Material Roll Compaction & Milling (Synthetic)

Version: 1.0 Publisher: Innovative Process Applications (IPA) License: Creative Commons Attribution 4.0 International (CC BY 4.0) Contact: Crestwood, IL, USA

This dataset is 100% synthetic and intended for educational use only. It was generated from published physical models and real compactor specifications — not measured on any real equipment, customer, or production batch. Do not use it for regulatory submissions, equipment validation, or commercial process design.

What's in this dataset

720 simulated dry granulation runs across three pharmaceutical model materials, three roll compactor geometries, two sealing systems, and two roll surfaces — spanning the full multi-factor design space described in the granulation literature.

Process inputs (what you control)

Column	Units	Description
`run_id`	—	Unique run identifier
`material`	—	Model material: MCC_101, Mannitol_SD, or MCC_Mannitol_Mix
`deformation_type`	—	Material deformation class: plastic, brittle, or mixed
`true_density_gcc`	g/cc	True (helium) density of the material
`compactor_config`	—	Machine geometry label (roll diameter × width)
`roll_diameter_mm`	mm	Roll diameter (120 or 250 mm — from published specs)
`roll_width_mm`	mm	Roll width (25 or 30 mm)
`sealing_system`	—	Side-sealing or rim-rolls
`roll_surface`	—	Smooth or knurled
`scf_kN_per_cm`	kN/cm	Specific compaction force
`gap_width_mm`	mm	Set gap width
`roll_speed_rpm`	rpm	Roll rotation speed
`feed_screw_rpm`	rpm	Feed screw speed

Intermediate physics (what the machine does)

Column	Units	Description
`densification_factor`	—	DF = drawn-in width / gap width (scales with roll diameter)
`nip_angle_deg`	°	Computed nip angle (depends on surface, friction, feed ratio)
`peak_pressure_MPa`	MPa	Estimated peak nip pressure

Quality responses (what you measure)

Column	Units	Description
`ribbon_rel_density`	—	Relative density (fraction of true density)
`ribbon_density_gcc`	g/cc	Absolute ribbon density
`ribbon_porosity`	—	1 − relative density
`density_CV_percent`	%	Across-width density coefficient of variation (uniformity)
`in_zinchuk_window`	Yes/No	Is ribbon RD in the 0.60–0.80 range for downstream tabletability?
`fines_fraction_pct`	%	Fraction of granules < 100 µm after milling (fines)
`granule_d50_um`	µm	Median granule size after oscillating mill
`throughput_kg_hr`	kg/hr	Mass throughput

Scientific basis

The physical model is grounded in the granulation fundamentals described in:

Szappanos-Csordás, K. (2018). Impact of material properties, process parameters and roll compactor design on roll compaction. Doctoral dissertation, Heinrich-Heine-Universität Düsseldorf.

Key concepts from Chapter 1 modeled here:

Three material deformation classes: MCC 101 (plastic), spray-dried mannitol (brittle), and their 1:1 mixture — the same model materials used in the dissertation's experimental design.
Densification factor (DF): DF = DW/GW increases with roll diameter (Equations 1–3 in the dissertation). Larger rolls → wider drawn-in width → higher densification at the same gap setting.
Nip angle dependency: knurled roll surfaces and higher material friction coefficients produce larger nip angles and therefore higher densification. Smooth rolls and lubricants decrease the nip angle.
Roll speed / dwell-time sensitivity: Plastic materials (MCC) are highly sensitive to roll speed — fast rolls reduce dwell time and ribbon density. Brittle materials (mannitol) show negligible roll speed sensitivity because particle fragmentation is rapid.
Sealing system effect: Rim-roll sealing produces more uniform ribbon density (lower CV%) and fewer fines compared to side-sealing plates.
Zinchuk tabletability criterion: Ribbons with relative density between 0.60–0.80 produce granules with appropriate characteristics for tableting. Below 0.60, ribbons are too weak; above 0.80, loss of compactibility occurs.
Fines fraction: Inversely related to ribbon density. Brittle materials produce more fines upon milling. Rim-roll sealing reduces bypass fines.

Machine specifications (roll diameters, widths, SCF ranges, sealing systems) are drawn from Table 1 of the dissertation, which catalogs real laboratory-scale roll compactors from multiple manufacturers.

The generator adds realistic measurement noise (±1.2% on ribbon density, ±0.5% on CV, ±2% on fines, ±25 µm on d50). Full generator source is in generate_dataset.py — reproducible with seed 2026.

What you can teach with it

Multi-factor DOE: analyze main effects and interactions of material type, machine design, and process parameters on ribbon and granule quality
Material science: compare brittle vs. plastic deformation behavior and their consequences for compaction and milling
Machine design selection: quantify the effect of roll diameter, sealing system, and roll surface on product quality
Quality-by-Design (QbD): define a design space that meets the Zinchuk criterion while minimizing fines and maximizing throughput
Classification & clustering: build classifiers for the Zinchuk window or cluster runs by quality profile
Scale-up reasoning: use the densification factor relationship to reason about transferring processes between 120 mm and 250 mm roll compactors

Cross-links (also published on)

Kaggle: [link after publication]
Hugging Face Datasets: [link after publication]
Zenodo (DOI): [link after publication]
GitHub: [link after publication]
IPA website: https://www.innovativeprocess.com

About IPA

Innovative Process Applications designs and manufactures twin-feed-screw roller compactors, mills, and size-reduction equipment for the pharmaceutical, nutraceutical, chemical, and food industries. Based in Crestwood, Illinois, IPA is a direct OEM alternative to legacy Fitzpatrick Chilsonator and FitzMill systems, with American manufacturing and direct engineer access. Learn more at innovativeprocess.com.

Citation

If you use this dataset in teaching, a notebook, a paper, or a blog post, please cite:

Innovative Process Applications (2026). Dry Granulation: Multi-Material Roll Compaction & Milling (Synthetic), v1.0. CC BY 4.0. https://www.innovativeprocess.com

Scientific basis:

Szappanos-Csordás, K. (2018). Impact of material properties, process parameters and roll compactor design on roll compaction. Doctoral dissertation, Heinrich-Heine-Universität Düsseldorf.

Version history

v1.0 (April 2026) — Initial release. 720 runs, 24 columns, 3 materials, 3 compactor geometries, 2 sealing systems, 2 roll surfaces.

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