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HumanProteinAtlas

ensembl_id string	gene string	gene_description string	uniprot list	chromosome string	position string	evidence string	hpa_evidence string	uniprot_evidence string	nextprot_evidence string	antibodies list	gene_synonyms list	protein_classes list	biological_processes list	molecular_functions list	disease_involvement list	subcellular_main_locations list	subcellular_additional_locations list	secretome_locations list	secretome_functions list	reliability_if string	reliability_ih string	reliability_mouse_brain string	interactions float64	ccd_protein string	ccd_transcript string	blood_expression_cluster string	brain_expression_cluster string	cell_line_expression_cluster string	single_cell_expression_cluster string	tissue_expression_cluster string	rna_tissue_specificity string	rna_tissue_distribution string	rna_tissue_specificity_score float64	rna_cell_line_specificity string	rna_cell_line_distribution string	rna_cell_line_specificity_score float64	rna_cancer_specificity string	rna_cancer_distribution string	rna_cancer_specificity_score float64	rna_single_cell_type_specificity string	rna_single_cell_type_distribution string	rna_single_cell_type_specificity_score float64	rna_blood_cell_specificity string	rna_blood_cell_distribution string	rna_blood_cell_specificity_score float64	prognostic_cancer_count int64	validated_prognostic_cancer_count int64	potential_prognostic_cancer_count int64	favorable_prognostic_cancers list	unfavorable_prognostic_cancers list	prognostic_cancers list	source_row_index int64	split_bucket int64
ENSG00000000003	TSPAN6	Tetraspanin 6	[ "O43657" ]	X	100627108-100639991	Evidence at protein level	Evidence at transcript level	Evidence at protein level	Evidence at protein level	[ "HPA004109" ]	[ "T245", "TM4SF6", "TSPAN-6" ]	[ "Predicted membrane proteins" ]	[]	[]	[]	[ "Cell Junctions", "Cytosol" ]	[ "Nucleoli fibrillar center" ]	[]	[]	Approved	Approved	null	2	null	null	Cluster 43: Non-specific - Transcription & Translation	Cluster 3: Choroid plexus - Cilium	Cluster 53: Squamous epithelial cells - Keratinization	Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization	Cluster 56: Ciliated tissues - Cilium organization	Low tissue specificity	Detected in many	null	Low cancer specificity	Detected in many	null	Low cancer specificity	Detected in all	null	Group enriched	Detected in many	5	Immune cell enhanced	Detected in some	null	3	0	3	[ "Kidney Renal Clear Cell Carcinoma" ]	[ "Head and Neck Squamous Cell Carcinoma", "Pancreatic Adenocarcinoma" ]	[ "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]	0	6
ENSG00000000005	TNMD	Tenomodulin	[ "Q9H2S6" ]	X	100584936-100599885	Evidence at protein level	Evidence at transcript level	Evidence at protein level	Evidence at protein level	[ "HPA034961", "HPA055634" ]	[ "BRICD4", "ChM1L", "myodulin", "TEM", "tendin" ]	[ "Predicted membrane proteins" ]	[]	[]	[]	[]	[]	[]	[]	null	Uncertain	null	1	null	null	null	Cluster 36: Choroid plexus - Mixed function	Cluster 34: Testis cancer - Unknown function	Cluster 94: Gonadal somatic cells - Mixed function	Cluster 14: Adipose tissue - Angiogenesis	Tissue enhanced	Detected in some	null	Group enriched	Detected in some	5	Low cancer specificity	Detected in some	null	Cell type enhanced	Detected in some	null	Not detected in immune cells	Not detected	null	0	0	0	[]	[]	[]	1	3
ENSG00000000419	DPM1	Dolichyl-phosphate mannosyltransferase subunit 1, catalytic	[ "O60762" ]	20	50934867-50959140	Evidence at protein level	Evidence at transcript level	Evidence at protein level	Evidence at protein level	[ "HPA051818" ]	[ "CDGIE", "MPDS" ]	[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins" ]	[]	[ "Glycosyltransferase", "Transferase" ]	[ "Congenital disorder of glycosylation", "Congenital muscular dystrophy", "Disease variant", "Dystroglycanopathy" ]	[]	[]	[]	[]	null	Approved	null	22	null	null	Cluster 33: Non-specific - ATP binding	Cluster 21: Non-specific - Metabolism	Cluster 62: Non-specific - Plasma proteins	Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal	Cluster 76: Non-specific - Metabolism	Low tissue specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Cell type enhanced	Detected in all	null	Low immune cell specificity	Detected in all	null	3	2	2	[]	[ "Head and Neck Squamous Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Thyroid Carcinoma" ]	[ "Head and Neck Squamous Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Thyroid Carcinoma" ]	2	6
ENSG00000000457	SCYL3	SCY1 like pseudokinase 3	[ "Q8IZE3" ]	1	169849631-169894267	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA005624", "HPA072383" ]	[ "PACE-1", "PACE1" ]	[ "Enzymes", "Predicted intracellular proteins" ]	[]	[]	[]	[ "Golgi apparatus", "Cytosol" ]	[]	[]	[]	Supported	Approved	null	23	null	null	Cluster 5: Non-specific - Cell proliferation	Cluster 50: Non-specific - Nucleic acid binding	Cluster 45: Non-specific - Nuclear processes	Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc	Cluster 61: Non-specific - Transcription	Low tissue specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cell type specificity	Detected in many	null	Low immune cell specificity	Detected in all	null	0	0	0	[]	[]	[]	3	8
ENSG00000000460	C1orf112	Chromosome 1 open reading frame 112	[ "Q9NSG2" ]	1	169662007-169854080	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA023778", "HPA024451" ]	[ "FLJ10706" ]	[ "Predicted intracellular proteins" ]	[]	[]	[]	[ "Nucleoplasm" ]	[ "Nucleoli" ]	[]	[]	Supported	Uncertain	null	16	null	null	Cluster 10: Non-specific - Membrane trafficking	Cluster 55: Non-specific - Transcription	Cluster 45: Non-specific - Nuclear processes	Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc	Cluster 61: Non-specific - Transcription	Tissue enhanced	Detected in many	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in many	null	Cell type enhanced	Detected in many	null	Low immune cell specificity	Detected in many	null	2	4	0	[]	[ "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]	[ "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]	4	7
ENSG00000000938	FGR	FGR proto-oncogene, Src family tyrosine kinase	[ "P09769" ]	1	27612064-27635185	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA002024" ]	[ "c-fgr", "p55c-fgr", "SRC2" ]	[ "Disease related genes", "Enzymes", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins" ]	[ "Immunity", "Innate immunity" ]	[ "Kinase", "Transferase", "Tyrosine-protein kinase" ]	[ "Proto-oncogene" ]	[ "Plasma membrane" ]	[ "Aggresome" ]	[]	[]	Approved	Enhanced	null	16	null	null	Cluster 37: Monocytes & Neutrophils - Innate immune response	Cluster 47: Endothelial cells - Vasculature	Cluster 55: Lymphoma - Immune response	Cluster 40: Monocytes & Neutrophils - Inflammatory signaling	Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response	Group enriched	Detected in many	6	Group enriched	Detected in some	16	Low cancer specificity	Detected in all	null	Cell type enhanced	Detected in some	null	Low immune cell specificity	Detected in all	null	2	0	2	[ "Breast Invasive Carcinoma" ]	[ "Rectum Adenocarcinoma" ]	[ "Breast Invasive Carcinoma", "Rectum Adenocarcinoma" ]	5	6
ENSG00000000971	CFH	Complement factor H	[ "P08603" ]	1	196651754-196752476	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "CAB016385", "CAB016769", "HPA038922", "HPA049176", "HPA053326" ]	[ "ARMD4", "ARMS1", "FHL1", "HF", "HF1", "HF2", "HUS" ]	[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Predicted secreted proteins" ]	[ "Complement alternate pathway", "Host-virus interaction", "Immunity", "Innate immunity" ]	[]	[ "Age-related macular degeneration", "Cancer-related genes", "Disease variant", "Hemolytic uremic syndrome" ]	[ "Vesicles" ]	[]	[ "Secreted to blood" ]	[ "Immunity" ]	Approved	Supported	null	9	null	null	Cluster 1: T-cells - Unknown function	Cluster 42: Choroid plexus - Mitochondria	Cluster 71: Lymphoma - Inflammatory response	Cluster 104: Brain endothelial cells - Blood brain barrier	Cluster 45: Liver - Metabolism & Coagulation	Tissue enriched	Detected in all	5	Cancer enhanced	Detected in many	null	Cancer enriched	Detected in all	8	Cell type enhanced	Detected in many	null	Immune cell enhanced	Detected in some	null	1	0	1	[]	[ "Glioblastoma Multiforme" ]	[ "Glioblastoma Multiforme" ]	6	6
ENSG00000001036	FUCA2	Alpha-L-fucosidase 2	[ "Q9BTY2" ]	6	143494812-143511720	Evidence at protein level	Evidence at transcript level	Evidence at protein level	Evidence at protein level	[ "HPA031659", "HPA031661" ]	[ "dJ20N2.5", "MGC1314" ]	[ "Enzymes", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins", "Predicted secreted proteins" ]	[]	[ "Glycosidase", "Hydrolase" ]	[]	[]	[]	[ "Secreted to blood" ]	[ "Enzyme" ]	null	Approved	null	16	null	null	Cluster 38: Monocytes & Neutrophils - Degranulation	Cluster 50: Non-specific - Nucleic acid binding	Cluster 28: Non-specific - Nuclear processes	Cluster 8: Non-specific - Secretory pathway	Cluster 69: Parathyroid gland - Mixed function	Tissue enhanced	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Cell type enhanced	Detected in all	null	Low immune cell specificity	Detected in all	null	4	2	3	[ "Kidney Renal Clear Cell Carcinoma" ]	[ "Glioblastoma Multiforme", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]	[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]	7	9
ENSG00000001084	GCLC	Glutamate-cysteine ligase catalytic subunit	[ "P48506" ]	6	53497341-53616970	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "CAB009569", "HPA036359", "HPA036360" ]	[ "GCS", "GLCL", "GLCLC" ]	[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins" ]	[ "Glutathione biosynthesis" ]	[ "Ligase" ]	[ "Disease variant", "Hereditary hemolytic anemia" ]	[ "Nucleoplasm" ]	[ "Nucleoli", "Cytosol" ]	[]	[]	Approved	Approved	null	7	null	null	Cluster 41: Basophils - Unknown function	Cluster 13: Oligodendrocytes - Mixed function	Cluster 7: Liver cancer - Metabolism	Cluster 69: Urothelial cells - Basic cellular functions	Cluster 45: Liver - Metabolism & Coagulation	Tissue enhanced	Detected in all	null	Cancer enhanced	Detected in all	null	Cancer enhanced	Detected in all	null	Cell type enhanced	Detected in many	null	Immune cell enhanced	Detected in many	null	4	0	4	[ "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]	[ "Kidney Renal Papillary Cell Carcinoma", "Lung Adenocarcinoma" ]	[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Lung Adenocarcinoma", "Rectum Adenocarcinoma" ]	8	2
ENSG00000001167	NFYA	Nuclear transcription factor Y subunit alpha	[ "P23511" ]	6	41072974-41102403	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "CAB009250", "HPA050779" ]	[ "CBF-B", "HAP2", "NF-YA" ]	[ "Predicted intracellular proteins", "Transcription factors" ]	[ "Biological rhythms", "Transcription", "Transcription regulation" ]	[ "Activator", "DNA-binding" ]	[]	[ "Nucleoplasm" ]	[]	[]	[]	Supported	Enhanced	null	32	null	null	Cluster 33: Non-specific - ATP binding	Cluster 11: White matter - Signal transduction	Cluster 28: Non-specific - Nuclear processes	Cluster 48: Neutrophils - Phagocytosis & degranulation	Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation	Low tissue specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Cell type enhanced	Detected in many	null	Low immune cell specificity	Detected in all	null	1	0	1	[ "Kidney Renal Clear Cell Carcinoma" ]	[]	[ "Kidney Renal Clear Cell Carcinoma" ]	9	8
ENSG00000001460	STPG1	Sperm tail PG-rich repeat containing 1	[ "Q5TH74" ]	1	24356999-24416934	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA024301" ]	[ "C1orf201", "FLJ33340", "MAPO2" ]	[ "Predicted intracellular proteins" ]	[ "Apoptosis" ]	[]	[]	[ "Nucleoplasm" ]	[]	[]	[]	Approved	null	null	null	null	null	Cluster 12: Non-specific - Mitochondrial translation	Cluster 52: Neurons & Synapses - Synaptic function	Cluster 37: Non-specific - mRNA processing	Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization	Cluster 48: Ciliated tissues - Cilium organization	Tissue enhanced	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Group enriched	Detected in many	4	Low immune cell specificity	Detected in some	null	2	0	2	[ "Kidney Renal Clear Cell Carcinoma" ]	[ "Glioblastoma Multiforme" ]	[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]	10	3
ENSG00000001461	NIPAL3	NIPA like domain containing 3	[ "Q6P499" ]	1	24415802-24472976	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA039978" ]	[ "DJ462O23.2", "NPAL3", "SLC57A5" ]	[ "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]	[]	[]	[]	[ "Nucleoplasm" ]	[]	[]	[]	Approved	Approved	null	13	null	null	Cluster 5: Non-specific - Cell proliferation	Cluster 26: Oligodendrocytes - Mixed function	Cluster 64: Connective tissue cells - ECM organization	Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid	Cluster 3: Oligodendrocytes - Myelination	Tissue enhanced	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Cell type enriched	Detected in many	4	Low immune cell specificity	Detected in all	null	2	0	2	[ "Kidney Renal Clear Cell Carcinoma" ]	[ "Liver Hepatocellular Carcinoma" ]	[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]	11	1
ENSG00000001497	LAS1L	LAS1 like ribosome biogenesis factor	[ "Q9Y4W2" ]	X	65438549-65534810	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA044431", "HPA061463" ]	[ "FLJ12525", "Las1" ]	[ "Disease related genes", "Essential proteins", "Human disease related genes", "Predicted intracellular proteins" ]	[ "rRNA processing" ]	[ "Hydrolase" ]	[ "Disease variant", "Intellectual disability", "Obesity" ]	[ "Nucleoplasm" ]	[ "Primary cilium transition zone", "Centriolar satellite", "Centrosome", "Basal body", "Cytosol" ]	[]	[]	Approved	Supported	null	51	null	null	Cluster 13: Non-specific - Mitochondria	Cluster 13: Oligodendrocytes - Mixed function	Cluster 36: Non-specific - mRNA processing	Cluster 56: Late spermatids - Spermiogenesis: Maturation	Cluster 3: Oligodendrocytes - Myelination	Low tissue specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Cell type enhanced	Detected in many	null	Low immune cell specificity	Detected in all	null	2	0	2	[ "Glioblastoma Multiforme", "Testicular Germ Cell Tumor" ]	[]	[ "Glioblastoma Multiforme", "Testicular Germ Cell Tumor" ]	12	8
ENSG00000001561	ENPP4	Ectonucleotide pyrophosphatase/phosphodiesterase 4	[ "Q9Y6X5" ]	6	46129989-46146688	Evidence at protein level	Evidence at transcript level	Evidence at protein level	Evidence at protein level	[ "HPA016594" ]	[ "AP3Aase", "KIAA0879", "NPP4" ]	[ "Enzymes", "Predicted membrane proteins" ]	[ "Blood coagulation", "Hemostasis" ]	[ "Hydrolase" ]	[]	[]	[]	[]	[]	null	Approved	null	11	null	null	Cluster 3: Non-specific - Nuclear processes	Cluster 28: Oligodendrocytes - Mixed function	Cluster 15: Kidney cancer - Membrane components	Cluster 37: Neutrophil progenitors - Granulopoiesis	Cluster 25: Non-specific - Basic cellular processes	Low tissue specificity	Detected in all	null	Low cancer specificity	Detected in many	null	Low cancer specificity	Detected in all	null	Cell type enhanced	Detected in many	null	Low immune cell specificity	Detected in many	null	2	2	1	[ "Kidney Renal Clear Cell Carcinoma" ]	[ "Lung Squamous Cell Carcinoma" ]	[ "Kidney Renal Clear Cell Carcinoma", "Lung Squamous Cell Carcinoma" ]	13	4
ENSG00000001617	SEMA3F	Semaphorin 3F	[ "Q13275" ]	3	50155045-50189075	Evidence at protein level	Evidence at transcript level	Evidence at transcript level	Evidence at protein level	[ "HPA035008" ]	[ "Sema4", "SEMAK" ]	[ "Plasma proteins", "Predicted intracellular proteins", "Predicted secreted proteins" ]	[]	[]	[]	[]	[]	[ "Secreted to blood" ]	[ "Developmental protein" ]	null	Approved	null	null	null	null	null	Cluster 38: Sub-cortical - Mixed function	Cluster 48: Adipocytes & Endothelial cells - Angiogenesis	Cluster 32: Endothelial cells - Angiogenesis & vascular immunity	Cluster 81: Squamous epithelium - Keratinization	Tissue enhanced	Detected in all	null	Cancer enhanced	Detected in all	null	Low cancer specificity	Detected in all	null	Cell type enhanced	Detected in many	null	Not detected in immune cells	Not detected	null	3	0	3	[ "Kidney Renal Clear Cell Carcinoma" ]	[ "Glioblastoma Multiforme", "Liver Hepatocellular Carcinoma" ]	[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]	14	2
ENSG00000001626	CFTR	CF transmembrane conductance regulator	[ "P13569" ]	7	117287120-117715971	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "CAB001951", "HPA021939", "HPA079652" ]	[ "ABC35", "ABCC7", "CF", "CFTR/MRP", "dJ760C5.1", "MRP7", "TNR-CFTR" ]	[ "Cancer-related genes", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]	[ "Ion transport", "Transport" ]	[ "Chloride channel", "Ion channel", "Isomerase" ]	[ "Cancer-related genes", "Disease variant", "FDA approved drug targets" ]	[]	[]	[]	[]	null	Enhanced	null	373	null	null	null	Cluster 11: White matter - Signal transduction	Cluster 57: Stomach & Colon cancer - Digestion	Cluster 38: Secretory epithelial cells - Exocrine secretion	Cluster 8: Pancreas - Proteolysis	Tissue enhanced	Detected in many	null	Cancer enhanced	Detected in many	null	Group enriched	Detected in many	4	Cell type enhanced	Detected in many	null	Not detected in immune cells	Not detected	null	2	0	2	[ "Colon Adenocarcinoma", "Lung Adenocarcinoma" ]	[]	[ "Colon Adenocarcinoma", "Lung Adenocarcinoma" ]	15	2
ENSG00000001630	CYP51A1	Cytochrome P450 family 51 subfamily A member 1	[ "Q16850" ]	7	92084987-92134803	Evidence at protein level	Evidence at transcript level	Evidence at protein level	Evidence at protein level	[ "HPA041325", "HPA043508" ]	[ "CP51", "CYP51", "CYPL1", "LDM", "P450-14DM", "P450L1" ]	[ "Enzymes", "FDA approved drug targets", "Metabolic proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]	[ "Cholesterol biosynthesis", "Cholesterol metabolism", "Lipid biosynthesis", "Lipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabolism" ]	[ "Monooxygenase", "Oxidoreductase" ]	[ "FDA approved drug targets" ]	[ "Endoplasmic reticulum" ]	[]	[]	[]	Approved	Approved	null	14	null	null	Cluster 13: Non-specific - Mitochondria	Cluster 49: Hindbrain - Mixed function	Cluster 57: Stomach & Colon cancer - Digestion	Cluster 83: Epicardial mesothelial cells - Basic cellular functions	Cluster 76: Non-specific - Metabolism	Tissue enhanced	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Cell type enhanced	Detected in many	null	Low immune cell specificity	Detected in all	null	3	0	3	[ "Kidney Renal Clear Cell Carcinoma" ]	[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Chromophobe" ]	[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma" ]	17	9
ENSG00000001631	KRIT1	KRIT1 ankyrin repeat containing	[ "O00522" ]	7	92197498-92246166	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA049606" ]	[ "CAM", "CCM1" ]	[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]	[ "Angiogenesis" ]	[]	[ "Disease variant" ]	[ "Vesicles" ]	[]	[]	[]	Uncertain	Supported	null	12	null	null	Cluster 5: Non-specific - Cell proliferation	Cluster 55: Non-specific - Transcription	Cluster 39: Non-specific - Transcription	Cluster 105: Non-specific - Mixed function	Cluster 69: Parathyroid gland - Mixed function	Low tissue specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Group enriched	Detected in many	9	Low immune cell specificity	Detected in all	null	3	0	3	[ "Kidney Renal Clear Cell Carcinoma" ]	[ "Kidney Chromophobe", "Pancreatic Adenocarcinoma" ]	[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]	18	8
ENSG00000002016	RAD52	RAD52 homolog, DNA repair protein	[ "P43351" ]	12	911736-990053	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA028957" ]	[]	[ "Cancer-related genes", "Predicted intracellular proteins" ]	[ "DNA damage", "DNA recombination", "DNA repair" ]	[ "DNA-binding" ]	[ "Cancer-related genes" ]	[ "Nuclear speckles" ]	[ "Plasma membrane" ]	[]	[]	Approved	null	null	24	null	null	Cluster 5: Non-specific - Cell proliferation	Cluster 11: White matter - Signal transduction	Cluster 38: Non-specific - Transcription	Cluster 36: Skeletal myocytes - Muscle excitation & contraction	Cluster 63: Non-specific - Basic cellular processes	Low tissue specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Cell type enhanced	Detected in many	null	Low immune cell specificity	Detected in all	null	2	0	2	[ "Rectum Adenocarcinoma" ]	[ "Kidney Chromophobe" ]	[ "Kidney Chromophobe", "Rectum Adenocarcinoma" ]	19	7
ENSG00000002330	BAD	BCL2 associated agonist of cell death	[ "Q92934" ]	11	64269830-64284704	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "CAB004205", "HPA028185", "HPA062105" ]	[ "BBC2", "BCL2L8" ]	[ "Cancer-related genes", "Predicted intracellular proteins", "RAS pathway related proteins" ]	[ "Apoptosis" ]	[]	[ "Cancer-related genes" ]	[ "Mitochondria" ]	[ "Principal piece", "End piece" ]	[]	[]	Enhanced	Approved	null	44	null	null	Cluster 29: Non-specific - Unknown function	Cluster 27: Non-specific - Mixed function	Cluster 24: Non-specific - Unknown function	Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func.	Cluster 68: Non-specific - Basic cellular processes	Low tissue specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Cell type enhanced	Detected in many	null	Low immune cell specificity	Detected in all	null	1	0	1	[]	[ "Liver Hepatocellular Carcinoma" ]	[ "Liver Hepatocellular Carcinoma" ]	20	3
ENSG00000002549	LAP3	Leucine aminopeptidase 3	[ "P28838" ]	4	17577198-17607972	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA029606", "HPA029607" ]	[ "LAP", "LAPEP", "PEPS" ]	[ "Enzymes", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins" ]	[]	[ "Aminopeptidase", "Hydrolase", "Protease" ]	[]	[ "Cytosol" ]	[ "Calyx", "Mid piece", "Principal piece" ]	[]	[]	Approved	Enhanced	null	15	null	No	Cluster 10: Non-specific - Membrane trafficking	Cluster 19: Astrocytes - Mixed function	Cluster 31: Non-specific - Antiviral immune response	Cluster 32: Endothelial cells - Angiogenesis & vascular immunity	Cluster 66: Lymphoid tissue - Immune response	Low tissue specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Cell type enhanced	Detected in many	null	Low immune cell specificity	Detected in all	null	1	0	1	[ "Kidney Renal Clear Cell Carcinoma" ]	[]	[ "Kidney Renal Clear Cell Carcinoma" ]	21	1
ENSG00000002586	CD99	CD99 molecule (Xg blood group)	[ "P14209" ]	X	2691187-2741309	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "CAB000020", "HPA035304" ]	[ "MIC2" ]	[ "CD markers", "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]	[ "Cell adhesion" ]	[]	[]	[ "Golgi apparatus" ]	[]	[]	[]	Approved	Supported	null	3	null	null	Cluster 13: Non-specific - Mitochondria	Cluster 39: Astrocytes - Mixed function	Cluster 12: Bone cancer - Neuronal signaling	Cluster 108: Fibroblasts - ECM organization	Cluster 12: Smooth muscle tissue - ECM organization	Low tissue specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Cell type enhanced	Detected in many	null	Low immune cell specificity	Detected in all	null	1	2	0	[]	[ "Lung Adenocarcinoma" ]	[ "Lung Adenocarcinoma" ]	22	3
ENSG00000002587	HS3ST1	Heparan sulfate-glucosamine 3-sulfotransferase 1	[ "O14792" ]	4	11393150-11429564	Evidence at protein level	Evidence at transcript level	Evidence at protein level	Evidence at protein level	[ "HPA002237" ]	[ "3OST1" ]	[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]	[]	[ "Transferase" ]	[]	[ "Vesicles" ]	[]	[ "Intracellular and membrane" ]	[ "Enzyme" ]	Approved	Approved	null	28	null	null	Cluster 8: Plasmacytoid DCs - Unknown function	Cluster 35: Non-specific - DNA binding	Cluster 53: Squamous epithelial cells - Keratinization	Cluster 100: Stratified epithelial cells - Barrier functions	Cluster 75: Ovary - Mixed function	Tissue enhanced	Detected in many	null	Cancer enhanced	Detected in many	null	Low cancer specificity	Detected in many	null	Cell type enhanced	Detected in many	null	Group enriched	Detected in some	36	1	0	1	[ "Kidney Renal Clear Cell Carcinoma" ]	[]	[ "Kidney Renal Clear Cell Carcinoma" ]	23	4
ENSG00000002726	AOC1	Amine oxidase copper containing 1	[ "P19801" ]	7	150824627-150861504	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA031032", "HPA031033" ]	[ "ABP", "ABP1", "DAO" ]	[ "Enzymes", "Metabolic proteins", "Predicted secreted proteins" ]	[]	[ "Heparin-binding", "Oxidoreductase" ]	[]	[]	[]	[ "Secreted in other tissues" ]	[ "Enzyme" ]	null	Approved	null	8	null	null	Cluster 36: Eosinophils - Protein ubiquitination	Cluster 46: Brainstem - Mixed function	Cluster 57: Stomach & Colon cancer - Digestion	Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier	Cluster 26: Kidney & Intestine - Metabolism	Group enriched	Detected in many	16	Cancer enhanced	Detected in many	null	Cancer enhanced	Detected in many	null	Cell type enhanced	Detected in many	null	Immune cell enriched	Detected in some	12	2	2	1	[ "Kidney Renal Clear Cell Carcinoma" ]	[ "Uterine Corpus Endometrial Carcinoma" ]	[ "Kidney Renal Clear Cell Carcinoma", "Uterine Corpus Endometrial Carcinoma" ]	24	7
ENSG00000002745	WNT16	Wnt family member 16	[ "Q9UBV4" ]	7	121325367-121341104	Evidence at protein level	Evidence at transcript level	Evidence at transcript level	Evidence at protein level	[]	[]	[ "Predicted intracellular proteins", "Predicted secreted proteins" ]	[ "Wnt signaling pathway" ]	[ "Developmental protein" ]	[]	[]	[]	[ "Secreted to extracellular matrix" ]	[ "Developmental protein" ]	null	null	null	null	null	null	Cluster 23: B-cells - Immunoglobulins	Cluster 23: Choroid plexus - Mixed function	Cluster 6: Leukemia - Signal transduction	Cluster 87: B-cells - Adaptive immunity: Humoral response	Cluster 37: Skin - Keratinization	Group enriched	Detected in some	4	Cancer enhanced	Detected in many	null	Low cancer specificity	Detected in some	null	Cell type enhanced	Detected in some	null	Group enriched	Detected in some	145	1	0	1	[]	[ "Glioblastoma Multiforme" ]	[ "Glioblastoma Multiforme" ]	25	1
ENSG00000002746	HECW1	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1	[ "Q76N89" ]	7	43112629-43566001	Evidence at protein level	Evidence at transcript level	Evidence at protein level	Evidence at protein level	[ "HPA007203", "HPA007593", "HPA007609" ]	[ "KIAA0322", "NEDL1" ]	[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]	[ "Ubl conjugation pathway" ]	[ "Transferase" ]	[]	[ "Nucleoli fibrillar center" ]	[ "Cytosol" ]	[]	[]	Approved	Uncertain	null	6	null	null	Cluster 20: Non-specific - DNA binding	Cluster 14: Neurons - Synaptic function	Cluster 7: Liver cancer - Metabolism	Cluster 109: Neurons - Neuronal signaling	Cluster 36: Brain & Liver - Signaling	Tissue enhanced	Detected in some	null	Low cancer specificity	Detected in many	null	Low cancer specificity	Detected in many	null	Cell type enhanced	Detected in many	null	Low immune cell specificity	Detected in some	null	2	0	2	[ "Glioblastoma Multiforme" ]	[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]	[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Glioblastoma Multiforme" ]	26	5
ENSG00000002822	MAD1L1	Mitotic arrest deficient 1 like 1	[ "Q9Y6D9" ]	7	1815793-2233243	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA003635", "CAB015338" ]	[ "HsMAD1", "MAD1", "PIG9", "TP53I9", "TXBP181" ]	[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]	[ "Cell cycle", "Cell division", "Mitosis" ]	[]	[ "Disease variant" ]	[ "Nucleoplasm", "Nuclear membrane" ]	[]	[]	[]	Supported	Supported	null	61	null	null	Cluster 9: T-regs - Cell cycle regulation	Cluster 11: White matter - Signal transduction	Cluster 67: Non-specific - Unknown function	Cluster 102: Non-specific - Mixed function	Cluster 68: Non-specific - Basic cellular processes	Low tissue specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Cancer enhanced	Detected in all	null	Cell type enhanced	Detected in many	null	Low immune cell specificity	Detected in all	null	3	0	3	[ "Kidney Renal Papillary Cell Carcinoma" ]	[ "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]	[ "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]	27	3
ENSG00000002834	LASP1	LIM and SH3 protein 1	[ "Q14847" ]	17	38869859-38921770	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA012072", "CAB022049" ]	[ "Lasp-1", "MLN50" ]	[ "Cancer-related genes", "Plasma proteins", "Predicted intracellular proteins" ]	[ "Ion transport", "Transport" ]	[ "Actin-binding" ]	[ "Cancer-related genes" ]	[ "Plasma membrane", "Cytosol" ]	[ "Golgi apparatus", "Focal adhesion sites" ]	[]	[]	Approved	Enhanced	null	35	null	null	Cluster 38: Monocytes & Neutrophils - Degranulation	Cluster 38: Sub-cortical - Mixed function	Cluster 27: Breast cancer - Unknown function	Cluster 29: Neutrophils - Innate immune cellular maintenance	Cluster 77: Intestine - Digestion	Low tissue specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Cell type enhanced	Detected in many	null	Low immune cell specificity	Detected in all	null	4	0	4	[ "Kidney Renal Clear Cell Carcinoma" ]	[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]	[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]	28	5
ENSG00000002919	SNX11	Sorting nexin 11	[ "Q9Y5W9" ]	17	48103357-48123601	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA044787", "HPA054660" ]	[]	[ "Predicted intracellular proteins" ]	[ "Protein transport", "Transport" ]	[]	[]	[ "Endoplasmic reticulum" ]	[ "Vesicles" ]	[]	[]	Approved	Approved	null	10	null	null	Cluster 28: Neutrophils - Unknown function	Cluster 13: Oligodendrocytes - Mixed function	Cluster 55: Lymphoma - Immune response	Cluster 97: Non-specific - Cellular respiration	Cluster 18: Lymphoid tissue - Immune response	Low tissue specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Cell type enhanced	Detected in many	null	Low immune cell specificity	Detected in all	null	3	0	3	[ "Kidney Renal Clear Cell Carcinoma" ]	[ "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]	[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]	29	5
ENSG00000002933	TMEM176A	Transmembrane protein 176A	[ "Q96HP8" ]	7	150800403-150805118	Evidence at protein level	Evidence at transcript level	Evidence at protein level	Evidence at protein level	[ "HPA008770" ]	[ "HCA112", "MS4B1" ]	[ "Predicted membrane proteins", "Transporters" ]	[]	[]	[]	[ "Mitochondria" ]	[]	[]	[]	Approved	Approved	null	12	null	null	Cluster 26: Monocytes - Plasma membrane proteins	Cluster 22: Non-specific - Mixed function	Cluster 64: Connective tissue cells - ECM organization	Cluster 1: Enterocytes - Absorption and Digestion	Cluster 16: Liver & Kidney - Metabolism	Group enriched	Detected in all	4	Cancer enhanced	Detected in many	null	Cancer enhanced	Detected in all	null	Cell type enhanced	Detected in many	null	Immune cell enhanced	Detected in many	null	2	0	2	[ "Kidney Renal Clear Cell Carcinoma" ]	[ "Rectum Adenocarcinoma" ]	[ "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]	30	4
ENSG00000003056	M6PR	Mannose-6-phosphate receptor, cation dependent	[ "P20645" ]	12	8940361-8949761	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "CAB034464", "HPA040445" ]	[ "CD-M6PR", "CD-MPR" ]	[ "FDA approved drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]	[ "Transport" ]	[ "Receptor" ]	[ "FDA approved drug targets" ]	[]	[]	[]	[]	null	Approved	null	14	null	null	Cluster 42: Non-specific - Vesicular transport	Cluster 21: Non-specific - Metabolism	Cluster 38: Non-specific - Transcription	Cluster 72: Macrophages - Phagocytosis & lysosomal degradation	Cluster 18: Lymphoid tissue - Immune response	Low tissue specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Cell type enhanced	Detected in all	null	Low immune cell specificity	Detected in all	null	1	0	1	[]	[ "Liver Hepatocellular Carcinoma" ]	[ "Liver Hepatocellular Carcinoma" ]	31	1
ENSG00000003096	KLHL13	Kelch like family member 13	[ "Q9P2N7" ]	X	117897813-118117340	Evidence at protein level	Evidence at transcript level	Evidence at protein level	Evidence at protein level	[ "HPA046039", "HPA059901" ]	[ "BKLHD2", "FLJ10262", "KIAA1309" ]	[ "Predicted intracellular proteins" ]	[ "Cell cycle", "Cell division", "Mitosis", "Ubl conjugation pathway" ]	[]	[]	[ "Cytosol" ]	[]	[]	[]	Approved	Approved	null	14	null	null	Cluster 22: Eosinophils - Transcription	Cluster 38: Sub-cortical - Mixed function	Cluster 17: Neuroblastoma - Neuronal signaling	Cluster 50: Renal epithelial cells - Ion transport and pH regulation	Cluster 75: Ovary - Mixed function	Tissue enhanced	Detected in many	null	Group enriched	Detected in many	5	Low cancer specificity	Detected in many	null	Cell type enhanced	Detected in many	null	Immune cell enhanced	Detected in some	null	4	0	4	[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]	[ "Liver Hepatocellular Carcinoma", "Stomach Adenocarcinoma" ]	[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Stomach Adenocarcinoma" ]	32	8
ENSG00000003137	CYP26B1	Cytochrome P450 family 26 subfamily B member 1	[ "Q9NR63" ]	2	72129238-72147862	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA012567" ]	[ "P450RAI-2" ]	[ "Disease related genes", "Metabolic proteins", "Predicted intracellular proteins" ]	[ "Lipid metabolism" ]	[ "Monooxygenase", "Oxidoreductase" ]	[ "Craniosynostosis", "Disease variant" ]	[ "Cytosol" ]	[]	[]	[]	Approved	Uncertain	null	14	No	No	null	Cluster 49: Hindbrain - Mixed function	Cluster 5: Rhabdoid - Unknown function	Cluster 94: Gonadal somatic cells - Mixed function	Cluster 2: Non-specific - Mixed function	Tissue enhanced	Detected in many	null	Cancer enhanced	Detected in many	null	Low cancer specificity	Detected in many	null	Group enriched	Detected in many	5	Not detected in immune cells	Not detected	null	2	0	2	[ "Kidney Renal Clear Cell Carcinoma" ]	[ "Liver Hepatocellular Carcinoma" ]	[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]	33	9
ENSG00000003147	ICA1	Islet cell autoantigen 1	[ "Q05084" ]	7	8113184-8262687	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA017646", "HPA061452" ]	[ "ICA69", "ICAp69" ]	[ "Predicted intracellular proteins", "Predicted membrane proteins" ]	[ "Neurotransmitter transport", "Transport" ]	[]	[]	[ "Vesicles", "Cytosol" ]	[]	[]	[]	Supported	Approved	null	8	null	null	Cluster 9: T-regs - Cell cycle regulation	Cluster 34: Non-specific - Mixed function	Cluster 17: Neuroblastoma - Neuronal signaling	Cluster 37: Neutrophil progenitors - Granulopoiesis	Cluster 8: Pancreas - Proteolysis	Low tissue specificity	Detected in all	null	Cancer enhanced	Detected in many	null	Low cancer specificity	Detected in all	null	Cell type enhanced	Detected in many	null	Immune cell enriched	Detected in many	6	1	0	1	[ "Kidney Renal Clear Cell Carcinoma" ]	[]	[ "Kidney Renal Clear Cell Carcinoma" ]	34	4
ENSG00000003393	ALS2	Alsin Rho guanine nucleotide exchange factor ALS2	[ "Q96Q42" ]	2	201700267-201782112	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA046588", "HPA075409" ]	[ "ALS2CR6" ]	[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]	[]	[ "Guanine-nucleotide releasing factor" ]	[ "Amyotrophic lateral sclerosis", "Neurodegeneration" ]	[ "Vesicles", "Cytosol" ]	[]	[]	[]	Approved	Enhanced	null	20	null	null	Cluster 46: Basophils - Proteolysis	Cluster 35: Non-specific - DNA binding	Cluster 49: HMC-1 - Innate immune response	Cluster 2: Cerebellar granular cells - Neuronal signaling	Cluster 27: Cerebellum - Synaptic function	Tissue enhanced	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Cell type enhanced	Detected in many	null	Group enriched	Detected in many	5	3	0	3	[ "Kidney Renal Clear Cell Carcinoma" ]	[ "Kidney Renal Papillary Cell Carcinoma", "Pancreatic Adenocarcinoma" ]	[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Pancreatic Adenocarcinoma" ]	36	5
ENSG00000003400	CASP10	Caspase 10	[ "Q92851" ]	2	201182872-201229428	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "CAB003780", "HPA017059" ]	[ "FLICE-2", "MCH4" ]	[ "Cancer-related genes", "Disease related genes", "Enzymes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins" ]	[ "Apoptosis" ]	[ "Hydrolase", "Protease", "Thiol protease" ]	[ "Cancer-related genes", "Disease variant" ]	[ "Golgi apparatus" ]	[ "Vesicles" ]	[]	[]	Approved	Approved	null	21	null	null	Cluster 2: Dendritic cells - Unknown function	Cluster 47: Endothelial cells - Vasculature	Cluster 51: Myeloma - Immunoglobulins	Cluster 37: Neutrophil progenitors - Granulopoiesis	Cluster 5: Spleen - Immune response	Low tissue specificity	Detected in all	null	Cancer enhanced	Detected in many	null	Low cancer specificity	Detected in all	null	Cell type enhanced	Detected in many	null	Low immune cell specificity	Detected in many	null	1	0	1	[]	[ "Liver Hepatocellular Carcinoma" ]	[ "Liver Hepatocellular Carcinoma" ]	37	8
ENSG00000003402	CFLAR	CASP8 and FADD like apoptosis regulator	[ "O15519" ]	2	201116154-201176687	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA019044", "CAB022157", "CAB025216" ]	[ "c-FLIP", "CASH", "CASP8AP1", "Casper", "cFLIP", "CLARP", "FLAME", "FLIP", "I-FLICE", "MRIT" ]	[ "Cancer-related genes", "Enzymes", "Predicted intracellular proteins" ]	[ "Apoptosis", "Host-virus interaction" ]	[]	[ "Cancer-related genes" ]	[ "Nucleoplasm", "Plasma membrane", "Cytosol" ]	[ "Nuclear bodies" ]	[]	[]	Supported	Uncertain	null	34	null	Yes	Cluster 35: Neutrophils - Protein binding	Cluster 25: Non-specific - Transcription	Cluster 55: Lymphoma - Immune response	Cluster 24: Neutrophils - Innate immunity signal integration	Cluster 14: Adipose tissue - Angiogenesis	Low tissue specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Cell type enhanced	Detected in all	null	Immune cell enriched	Detected in all	4	2	0	2	[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]	[]	[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]	38	1
ENSG00000003509	NDUFAF7	NADH:ubiquinone oxidoreductase complex assembly factor 7	[ "Q7L592" ]	2	37231631-37253403	Evidence at protein level	Evidence at transcript level	Evidence at protein level	Evidence at protein level	[ "HPA045217" ]	[ "C2orf56", "MidA", "PRO1853" ]	[ "Disease related genes", "Enzymes", "Potential drug targets", "Predicted intracellular proteins" ]	[]	[ "Methyltransferase", "Transferase" ]	[]	[]	[]	[]	[]	null	Uncertain	null	8	null	null	Cluster 30: Non-specific - DNA binding	Cluster 52: Neurons & Synapses - Synaptic function	Cluster 26: Non-specific - Mitochondria & RNA binding	Cluster 53: Late primary spermatocytes - Meiotic division & transition	Cluster 39: Testis - Nuclear processes	Tissue enhanced	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Cell type enhanced	Detected in many	null	Low immune cell specificity	Detected in all	null	1	0	1	[]	[ "Liver Hepatocellular Carcinoma" ]	[ "Liver Hepatocellular Carcinoma" ]	40	4
ENSG00000003756	RBM5	RNA binding motif protein 5	[ "P52756" ]	3	50088919-50119021	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA017335", "HPA018011" ]	[ "H37", "LUCA-15", "LUCA15" ]	[ "Predicted intracellular proteins" ]	[ "Apoptosis", "mRNA processing", "mRNA splicing" ]	[ "RNA-binding" ]	[]	[ "Nucleoplasm" ]	[ "Perinuclear theca", "Flagellar centriole", "Mid piece", "Principal piece", "End piece" ]	[]	[]	Supported	Approved	null	34	null	null	Cluster 35: Neutrophils - Protein binding	Cluster 28: Oligodendrocytes - Mixed function	Cluster 8: Non-specific - Basic cellular processes	Cluster 7: Non-specific - Transcription	Cluster 64: Non-specific - Transcription	Low tissue specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Cell type enhanced	Detected in many	null	Low immune cell specificity	Detected in all	null	3	0	3	[ "Glioblastoma Multiforme", "Kidney Renal Papillary Cell Carcinoma", "Pancreatic Adenocarcinoma" ]	[]	[ "Glioblastoma Multiforme", "Kidney Renal Papillary Cell Carcinoma", "Pancreatic Adenocarcinoma" ]	41	5
ENSG00000003987	MTMR7	Myotubularin related protein 7	[ "Q9Y216" ]	8	17296794-17413528	Evidence at protein level	Evidence at transcript level	Evidence at protein level	Evidence at protein level	[ "HPA075682" ]	[]	[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]	[ "Lipid metabolism" ]	[ "Hydrolase" ]	[]	[ "Nucleoplasm", "Cytosol" ]	[]	[]	[]	Approved	null	null	13	null	null	null	Cluster 34: Non-specific - Mixed function	Cluster 71: Lymphoma - Inflammatory response	Cluster 79: Photoreceptor cells - Phototransduction	Cluster 46: Brain & retina - Neuronal signaling	Tissue enhanced	Detected in many	null	Cancer enhanced	Detected in many	null	Low cancer specificity	Detected in many	null	Cell type enhanced	Detected in many	null	Not detected in immune cells	Not detected	null	2	0	2	[ "Glioblastoma Multiforme", "Pancreatic Adenocarcinoma" ]	[]	[ "Glioblastoma Multiforme", "Pancreatic Adenocarcinoma" ]	42	4
ENSG00000003989	SLC7A2	Solute carrier family 7 member 2	[ "P52569" ]	8	17497088-17570573	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA009277" ]	[ "ATRC2", "CAT-2", "HCAT2" ]	[ "Metabolic proteins", "Predicted membrane proteins", "Transporters" ]	[ "Amino-acid transport", "Transport" ]	[]	[]	[ "Plasma membrane" ]	[ "Cell Junctions" ]	[]	[]	Supported	null	null	5	null	null	null	Cluster 8: Immune cells - Immune response	Cluster 10: Ciliated cells - Ion channel activity	Cluster 51: Secretory epithelial cells - Mixed function	Cluster 76: Non-specific - Metabolism	Tissue enhanced	Detected in many	null	Low cancer specificity	Detected in many	null	Cancer enhanced	Detected in many	null	Cell type enhanced	Detected in many	null	Not detected in immune cells	Not detected	null	1	0	1	[]	[ "Stomach Adenocarcinoma" ]	[ "Stomach Adenocarcinoma" ]	43	7
ENSG00000004059	ARF5	ADP ribosylation factor 5	[ "P84085" ]	7	127588386-127591700	Evidence at protein level	Evidence at transcript level	Evidence at protein level	Evidence at protein level	[]	[]	[ "Plasma proteins", "Predicted intracellular proteins" ]	[ "ER-Golgi transport", "Protein transport", "Transport" ]	[]	[]	[]	[]	[]	[]	null	null	null	33	null	null	Cluster 26: Monocytes - Plasma membrane proteins	Cluster 14: Neurons - Synaptic function	Cluster 39: Non-specific - Transcription	Cluster 97: Non-specific - Cellular respiration	Cluster 68: Non-specific - Basic cellular processes	Low tissue specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Cell type enhanced	Detected in all	null	Low immune cell specificity	Detected in all	null	1	0	1	[]	[ "Liver Hepatocellular Carcinoma" ]	[ "Liver Hepatocellular Carcinoma" ]	44	8
ENSG00000004139	SARM1	Sterile alpha and TIR motif containing 1	[ "Q6SZW1" ]	17	28364356-28404049	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA024359", "HPA024759" ]	[ "KIAA0524", "SAMD2", "SARM" ]	[ "Enzymes", "Predicted intracellular proteins" ]	[ "Differentiation", "Immunity", "Innate immunity", "Neurogenesis" ]	[ "Hydrolase" ]	[]	[ "Mitochondria" ]	[]	[]	[]	Supported	Uncertain	null	9	null	null	null	Cluster 15: Non-specific - Transcription	Cluster 72: Neuronal - Signal transduction	Cluster 72: Macrophages - Phagocytosis & lysosomal degradation	Cluster 64: Non-specific - Transcription	Low tissue specificity	Detected in many	null	Low cancer specificity	Detected in many	null	Cancer enhanced	Detected in many	null	Cell type enhanced	Detected in many	null	Not detected in immune cells	Not detected	null	2	0	2	[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]	[]	[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]	45	5
ENSG00000004142	POLDIP2	DNA polymerase delta interacting protein 2	[ "Q9Y2S7" ]	17	28346633-28357527	Evidence at protein level	Evidence at transcript level	Evidence at protein level	Evidence at protein level	[ "HPA007700" ]	[ "DKFZP586F1524", "PDIP38" ]	[ "Essential proteins", "Predicted intracellular proteins" ]	[ "DNA damage", "DNA repair" ]	[]	[]	[ "Mitochondria" ]	[]	[]	[]	Approved	null	null	32	null	null	Cluster 25: Non-specific - Unknown function	Cluster 32: Cerebral cortex - Mixed function	Cluster 27: Breast cancer - Unknown function	Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization	Cluster 25: Non-specific - Basic cellular processes	Tissue enhanced	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Cell type enhanced	Detected in all	null	Low immune cell specificity	Detected in all	null	2	0	2	[]	[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Liver Hepatocellular Carcinoma" ]	[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Liver Hepatocellular Carcinoma" ]	46	8
ENSG00000004455	AK2	Adenylate kinase 2	[ "P54819" ]	1	33007986-33080996	Evidence at protein level	Evidence at transcript level	Evidence at protein level	Evidence at protein level	[ "HPA018479", "CAB079913" ]	[]	[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins" ]	[]	[ "Kinase", "Transferase" ]	[ "Disease variant", "SCID" ]	[ "Mitochondria" ]	[]	[]	[]	Approved	Approved	null	16	null	null	Cluster 29: Non-specific - Unknown function	Cluster 6: Non-specific - Immune response	Cluster 37: Non-specific - mRNA processing	Cluster 97: Non-specific - Cellular respiration	Cluster 76: Non-specific - Metabolism	Low tissue specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Cell type enhanced	Detected in many	null	Low immune cell specificity	Detected in all	null	4	0	4	[ "Kidney Renal Clear Cell Carcinoma" ]	[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]	[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]	48	5
ENSG00000004468	CD38	CD38 molecule	[ "P28907" ]	4	15778275-15853232	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "CAB002493", "HPA022132", "CAB025255", "HPA052381" ]	[ "cADPR1" ]	[ "Cancer-related genes", "CD markers", "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]	[]	[ "Hydrolase", "Receptor", "Transferase" ]	[ "Cancer-related genes", "Diabetes mellitus" ]	[ "Plasma membrane" ]	[]	[]	[]	Supported	Enhanced	null	3	null	null	Cluster 14: Non-specific - Unknown function	Cluster 46: Brainstem - Mixed function	Cluster 46: Lymphoma - Humoral immune response	Cluster 44: Plasma cells - Antibody production & secretion	Cluster 51: Lymphoid tissue - Adaptive immune response	Tissue enhanced	Detected in many	null	Group enriched	Detected in some	15	Low cancer specificity	Detected in many	null	Cell type enhanced	Detected in many	null	Immune cell enhanced	Detected in many	null	2	0	2	[ "Head and Neck Squamous Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]	[]	[ "Head and Neck Squamous Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]	49	7
ENSG00000004478	FKBP4	FKBP prolyl isomerase 4	[ "Q02790" ]	12	2794970-2805423	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA006148", "CAB017441", "HPA062857" ]	[ "FKBP52", "FKBP59" ]	[ "Enzymes", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins" ]	[]	[ "Chaperone", "Isomerase", "Rotamase" ]	[]	[ "Cytosol" ]	[ "Nucleoplasm" ]	[]	[]	Supported	Supported	null	57	null	null	Cluster 43: Non-specific - Transcription & Translation	Cluster 55: Non-specific - Transcription	Cluster 27: Breast cancer - Unknown function	Cluster 75: Non-specific - Chaperones and protein folding	Cluster 67: Testis - Mixed function	Low tissue specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Cell type enhanced	Detected in many	null	Low immune cell specificity	Detected in all	null	2	2	1	[]	[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]	[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]	50	2
ENSG00000004534	RBM6	RNA binding motif protein 6	[ "P78332" ]	3	49940007-50100045	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA026272", "HPA027164" ]	[ "3G2", "DEF-3", "DEF3", "g16", "NY-LU-12" ]	[ "Cancer-related genes", "Plasma proteins", "Predicted intracellular proteins" ]	[]	[ "RNA-binding" ]	[ "Cancer-related genes" ]	[ "Nuclear speckles" ]	[ "Cytoplasmic bodies" ]	[]	[]	Approved	Enhanced	null	37	null	null	Cluster 5: Non-specific - Cell proliferation	Cluster 4: Non-specific - mRNA splicing & Cell cycle	Cluster 8: Non-specific - Basic cellular processes	Cluster 87: B-cells - Adaptive immunity: Humoral response	Cluster 64: Non-specific - Transcription	Low tissue specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cell type specificity	Detected in all	null	Low immune cell specificity	Detected in all	null	2	0	2	[ "Pancreatic Adenocarcinoma" ]	[ "Kidney Renal Clear Cell Carcinoma" ]	[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]	52	4
ENSG00000004700	RECQL	RecQ like helicase	[ "P46063" ]	12	21468910-21501669	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "CAB009743", "HPA030960", "HPA030961", "HPA064259", "CAB080253" ]	[ "RecQ1", "RecQL1" ]	[ "Enzymes", "Plasma proteins", "Predicted intracellular proteins" ]	[]	[ "DNA-binding", "Helicase", "Hydrolase", "Isomerase" ]	[ "Disease variant" ]	[ "Nucleoplasm" ]	[]	[]	[]	Supported	Enhanced	null	21	null	null	Cluster 33: Non-specific - ATP binding	Cluster 28: Oligodendrocytes - Mixed function	Cluster 38: Non-specific - Transcription	Cluster 17: Non-specific - RNA processing	Cluster 66: Lymphoid tissue - Immune response	Low tissue specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Cell type enhanced	Detected in many	null	Low immune cell specificity	Detected in all	null	1	0	1	[]	[ "Lung Adenocarcinoma" ]	[ "Lung Adenocarcinoma" ]	54	9
ENSG00000004766	VPS50	VPS50 subunit of EARP/GARPII complex	[ "Q96JG6" ]	7	93232340-93361123	Evidence at protein level	Evidence at transcript level	Evidence at protein level	Evidence at protein level	[ "HPA026679" ]	[ "CCDC132", "DKFZp313I2429", "FLJ20097", "KIAA1861", "VPS54L" ]	[ "Disease related genes", "Predicted intracellular proteins" ]	[ "Protein transport", "Transport" ]	[]	[ "Epilepsy", "Intellectual disability", "Intrahepatic cholestasis" ]	[ "Plasma membrane", "Cytosol" ]	[ "Primary cilium", "Basal body", "Mid piece", "Principal piece", "End piece" ]	[]	[]	Uncertain	Approved	null	18	null	null	Cluster 33: Non-specific - ATP binding	Cluster 31: Non-specific - Transcription	Cluster 39: Non-specific - Transcription	Cluster 7: Non-specific - Transcription	Cluster 38: Non-specific - Basic cellular processes	Low tissue specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cell type specificity	Detected in many	null	Low immune cell specificity	Detected in all	null	2	0	2	[]	[ "Colon Adenocarcinoma", "Liver Hepatocellular Carcinoma" ]	[ "Colon Adenocarcinoma", "Liver Hepatocellular Carcinoma" ]	55	9
ENSG00000004776	HSPB6	Heat shock protein family B (small) member 6	[ "O14558" ]	19	35754566-35758079	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "CAB001974", "HPA044153", "HPA054811" ]	[ "FLJ32389", "Hsp20", "PPP1R91" ]	[ "Predicted intracellular proteins" ]	[ "Stress response" ]	[ "Chaperone" ]	[]	[ "Mitochondria", "Cytosol" ]	[ "Nuclear speckles" ]	[ "Intracellular and membrane" ]	[ "Other" ]	Supported	Enhanced	null	4	null	null	null	Cluster 19: Astrocytes - Mixed function	Cluster 44: Connective tissue cells - ECM organization	Cluster 62: Smooth muscle cells - Muscle contraction	Cluster 25: Non-specific - Basic cellular processes	Tissue enhanced	Detected in many	null	Cancer enhanced	Detected in many	null	Cancer enhanced	Detected in all	null	Cell type enhanced	Detected in many	null	Not detected in immune cells	Not detected	null	0	0	0	[]	[]	[]	56	2
ENSG00000004777	ARHGAP33	Rho GTPase activating protein 33	[ "O14559" ]	19	35774532-35788822	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA030117", "HPA030118" ]	[ "FLJ39019", "SNX26", "TCGAP" ]	[ "Predicted intracellular proteins" ]	[ "Protein transport", "Transport" ]	[ "GTPase activation" ]	[]	[ "Plasma membrane" ]	[ "Actin filaments", "Cytosol" ]	[]	[]	Approved	Supported	null	2	null	null	null	Cluster 51: Neurons - Mixed function	Cluster 10: Ciliated cells - Ion channel activity	Cluster 27: Non-specific - Cell proliferation	Cluster 67: Testis - Mixed function	Low tissue specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Cancer enhanced	Detected in all	null	Cell type enhanced	Detected in many	null	Not detected in immune cells	Not detected	null	1	0	1	[]	[ "Kidney Renal Clear Cell Carcinoma" ]	[ "Kidney Renal Clear Cell Carcinoma" ]	57	6
ENSG00000004779	NDUFAB1	NADH:ubiquinone oxidoreductase subunit AB1	[ "O14561" ]	16	23581014-23596316	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA054364", "HPA076020" ]	[ "ACP", "ACP1", "FASN2A", "SDAP" ]	[ "Essential proteins", "Metabolic proteins", "Predicted intracellular proteins" ]	[ "Electron transport", "Fatty acid biosynthesis", "Fatty acid metabolism", "Lipid biosynthesis", "Lipid metabolism", "Respiratory chain", "Transport" ]	[]	[]	[ "Mitochondria" ]	[]	[]	[]	Supported	Approved	null	60	No	No	Cluster 13: Non-specific - Mitochondria	Cluster 21: Non-specific - Metabolism	Cluster 54: Non-specific - Transcription	Cluster 97: Non-specific - Cellular respiration	Cluster 52: Non-specific - Cellular respiration	Tissue enhanced	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Cell type enhanced	Detected in all	null	Low immune cell specificity	Detected in all	null	1	0	1	[]	[ "Breast Invasive Carcinoma" ]	[ "Breast Invasive Carcinoma" ]	58	7
ENSG00000004799	PDK4	Pyruvate dehydrogenase kinase 4	[ "Q16654" ]	7	95583499-95596516	Evidence at protein level	Evidence at transcript level	Evidence at protein level	Evidence at protein level	[ "HPA056731" ]	[]	[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]	[]	[ "Kinase", "Transferase" ]	[]	[]	[]	[]	[]	null	Approved	null	2	null	null	Cluster 25: Non-specific - Unknown function	Cluster 36: Choroid plexus - Mixed function	Cluster 44: Connective tissue cells - ECM organization	Cluster 103: Non-specific - Basic cellular processes	Cluster 63: Non-specific - Basic cellular processes	Tissue enhanced	Detected in all	null	Cancer enhanced	Detected in many	null	Group enriched	Detected in all	4	Cell type enhanced	Detected in many	null	Group enriched	Detected in many	11	5	2	4	[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]	[ "Kidney Renal Papillary Cell Carcinoma", "Stomach Adenocarcinoma" ]	[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Stomach Adenocarcinoma" ]	59	2
ENSG00000004809	SLC22A16	Solute carrier family 22 member 16	[ "Q86VW1" ]	6	110424687-110476641	Evidence at protein level	Evidence at transcript level	Evidence at protein level	Evidence at protein level	[ "HPA036902" ]	[ "CT2", "FLIPT2", "OAT6", "OKB1" ]	[ "Metabolic proteins", "Predicted membrane proteins", "Transporters" ]	[ "Differentiation", "Ion transport", "Spermatogenesis", "Transport" ]	[ "Developmental protein" ]	[]	[ "Plasma membrane", "Cytosol" ]	[]	[]	[]	Approved	Uncertain	null	2	null	null	Cluster 26: Monocytes - Plasma membrane proteins	null	Cluster 14: Myeloid leukemia - Innate immune response	Cluster 66: Erythroid cells - Erythroid differentiation and maturation	Cluster 44: Bone marrow - Nuclear processes	Group enriched	Detected in some	5	Cancer enriched	Detected in single	11	Cancer enriched	Detected in single	7	Cell type enhanced	Detected in some	null	Immune cell enhanced	Detected in some	null	0	0	0	[]	[]	[]	60	6
ENSG00000004838	ZMYND10	Zinc finger MYND-type containing 10	[ "O75800" ]	3	50341110-50345732	Evidence at protein level	Evidence at transcript level	Evidence at protein level	Evidence at protein level	[ "HPA035255" ]	[ "BLU", "CILD22", "DNAAF7" ]	[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]	[]	[]	[ "Ciliopathy", "Disease variant", "Kartagener syndrome", "Primary ciliary dyskinesia" ]	[ "Plasma membrane", "Basal body" ]	[ "Cytosol" ]	[]	[]	Approved	null	null	12	null	null	null	Cluster 3: Choroid plexus - Cilium	Cluster 10: Ciliated cells - Ion channel activity	Cluster 107: Ciliated cells - Cilia assembly & function	Cluster 56: Ciliated tissues - Cilium organization	Group enriched	Detected in many	13	Low cancer specificity	Detected in many	null	Cancer enhanced	Detected in many	null	Cell type enhanced	Detected in many	null	Immune cell enhanced	Detected in single	null	2	0	2	[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Papillary Cell Carcinoma" ]	[]	[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Papillary Cell Carcinoma" ]	61	1
ENSG00000004846	ABCB5	ATP binding cassette subfamily B member 5	[ "Q2M3G0" ]	7	20615667-20777038	Evidence at protein level	Evidence at transcript level	Evidence at protein level	Evidence at protein level	[]	[ "ABCB5alpha", "ABCB5beta", "EST422562" ]	[ "Enzymes", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]	[ "Differentiation", "Transport" ]	[ "Translocase" ]	[]	[]	[]	[]	[]	null	null	null	null	null	null	null	Cluster 48: Non-specific - Mixed function	Cluster 9: Skin cancer - Melanin biosynthesis	Cluster 30: Epididymal principal cells - Sperm storage microenvironment	Cluster 50: Epididymis - Male reproductive secretion	Tissue enriched	Detected in some	10	Cancer enriched	Detected in some	13	Group enriched	Detected in some	13	Group enriched	Detected in many	4	Not detected in immune cells	Not detected	null	1	0	1	[]	[ "Kidney Renal Clear Cell Carcinoma" ]	[ "Kidney Renal Clear Cell Carcinoma" ]	62	4
ENSG00000004848	ARX	Aristaless related homeobox	[ "Q96QS3" ]	X	25003694-25016420	Evidence at protein level	Evidence at transcript level	Evidence at protein level	Evidence at protein level	[]	[ "CT121", "EIEE1", "ISSX", "MRX29", "MRX32", "MRX33", "MRX36", "MRX38", "MRX43", "MRX54", "MRX76", "MRX87", "MRXS1", "PRTS" ]	[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Transcription factors" ]	[ "Differentiation", "Neurogenesis", "Transcription", "Transcription regulation" ]	[ "Developmental protein", "DNA-binding" ]	[ "Disease variant", "Epilepsy", "Intellectual disability", "Lissencephaly" ]	[]	[]	[]	[]	null	null	null	7	null	null	null	Cluster 53: Neurons - Mixed function	Cluster 12: Bone cancer - Neuronal signaling	Cluster 94: Gonadal somatic cells - Mixed function	Cluster 75: Ovary - Mixed function	Group enriched	Detected in some	5	Cancer enriched	Detected in some	6	Low cancer specificity	Detected in many	null	Cell type enhanced	Detected in some	null	Not detected in immune cells	Not detected	null	2	0	2	[]	[ "Glioblastoma Multiforme", "Uterine Corpus Endometrial Carcinoma" ]	[ "Glioblastoma Multiforme", "Uterine Corpus Endometrial Carcinoma" ]	63	1
ENSG00000004864	SLC25A13	Solute carrier family 25 member 13	[ "Q9UJS0" ]	7	96120220-96322147	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA018997" ]	[ "ARALAR2", "CITRIN", "CTLN2" ]	[ "Disease related genes", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Transporters" ]	[ "Transport" ]	[]	[ "Disease variant", "Intrahepatic cholestasis" ]	[ "Mitochondria" ]	[]	[]	[]	Supported	Enhanced	null	31	null	null	Cluster 25: Non-specific - Unknown function	Cluster 28: Oligodendrocytes - Mixed function	Cluster 39: Non-specific - Transcription	Cluster 31: Neutrophils - Chemotaxis & Apoptosis	Cluster 16: Liver & Kidney - Metabolism	Tissue enriched	Detected in all	5	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Cell type enhanced	Detected in many	null	Low immune cell specificity	Detected in many	null	1	0	1	[ "Kidney Renal Clear Cell Carcinoma" ]	[]	[ "Kidney Renal Clear Cell Carcinoma" ]	64	2
ENSG00000004866	ST7	Suppression of tumorigenicity 7	[ "Q9NRC1" ]	7	116953238-117230176	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA038325", "HPA038326" ]	[ "ETS7q", "FAM4A", "FAM4A1", "HELG", "RAY1", "SEN4", "TSG7" ]	[ "Predicted intracellular proteins", "Predicted membrane proteins" ]	[]	[]	[]	[ "Nucleoplasm" ]	[ "Cytosol" ]	[]	[]	Supported	Approved	null	26	No	No	Cluster 5: Non-specific - Cell proliferation	Cluster 35: Non-specific - DNA binding	Cluster 39: Non-specific - Transcription	Cluster 88: Proximal tubular cells - Transmembrane transport	Cluster 22: Epididymis - Mixed function	Low tissue specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Cell type enhanced	Detected in many	null	Low immune cell specificity	Detected in many	null	2	0	2	[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]	[]	[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]	65	4
ENSG00000004897	CDC27	Cell division cycle 27	[ "P30260" ]	17	47117703-47189422	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "CAB016315", "HPA028129", "HPA052399", "HPA065835" ]	[ "ANAPC3", "APC3", "D0S1430E", "D17S978E", "NUC2" ]	[ "Cancer-related genes", "Essential proteins", "Plasma proteins", "Predicted intracellular proteins" ]	[ "Ubl conjugation pathway" ]	[]	[ "Cancer-related genes" ]	[ "Nucleoplasm" ]	[]	[]	[]	Enhanced	Supported	null	114	null	Yes	Cluster 5: Non-specific - Cell proliferation	Cluster 31: Non-specific - Transcription	Cluster 27: Breast cancer - Unknown function	Cluster 103: Non-specific - Basic cellular processes	Cluster 61: Non-specific - Transcription	Low tissue specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Cell type enhanced	Detected in all	null	Low immune cell specificity	Detected in all	null	4	2	3	[ "Kidney Renal Clear Cell Carcinoma" ]	[ "Liver Hepatocellular Carcinoma", "Ovary Serous Cystadenocarcinoma", "Pancreatic Adenocarcinoma" ]	[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Ovary Serous Cystadenocarcinoma", "Pancreatic Adenocarcinoma" ]	66	6
ENSG00000004939	SLC4A1	Solute carrier family 4 member 1 (Diego blood group)	[ "P02730" ]	17	44248390-44268141	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA015584", "CAB034438", "HPA063911" ]	[ "AE1", "CD233", "DI", "EPB3", "FR", "RTA1A", "SW", "WD", "WR" ]	[ "Blood group antigen proteins", "CD markers", "Disease related genes", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted membrane proteins", "Transporters" ]	[ "Anion exchange", "Ion transport", "Transport" ]	[ "Blood group antigen" ]	[ "Disease variant", "Elliptocytosis", "Hereditary hemolytic anemia" ]	[]	[]	[]	[]	null	Enhanced	null	15	null	null	null	Cluster 48: Non-specific - Mixed function	Cluster 47: Leukemia - Hemostasis	Cluster 66: Erythroid cells - Erythroid differentiation and maturation	Cluster 15: Bone marrow - Innate immune response	Tissue enriched	Detected in some	10	Cancer enriched	Detected in single	62	Cancer enriched	Detected in many	56	Group enriched	Detected in some	38	Not detected in immune cells	Not detected	null	0	0	0	[]	[]	[]	67	2
ENSG00000004948	CALCR	Calcitonin receptor	[]	7	93424486-93574730	Evidence at protein level	Evidence at protein level	null	null	[ "HPA028962", "HPA061428" ]	[ "CT-R", "CTR" ]	[ "Human disease related genes", "Predicted membrane proteins" ]	[]	[]	[]	[ "Cell Junctions" ]	[ "Vesicles", "Centriolar satellite" ]	[]	[]	Approved	Enhanced	Supported	2	null	null	null	Cluster 56: Hypothalamus - Neuropeptide signaling	Cluster 15: Kidney cancer - Membrane components	Cluster 50: Renal epithelial cells - Ion transport and pH regulation	Cluster 72: Kidney - Transmembrane transport	Tissue enhanced	Detected in some	null	Cancer enhanced	Detected in some	null	Group enriched	Detected in some	5	Cell type enhanced	Detected in some	null	Not detected in immune cells	Not detected	null	0	0	0	[]	[]	[]	68	1
ENSG00000004961	HCCS	Holocytochrome c synthase	[ "P53701" ]	X	11111301-11123086	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA002946" ]	[ "CCHL", "MLS" ]	[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins" ]	[]	[ "Lyase" ]	[ "Disease variant", "Microphthalmia" ]	[ "Mitochondria" ]	[ "Cytosol" ]	[]	[]	Enhanced	Approved	null	22	null	null	Cluster 10: Non-specific - Membrane trafficking	Cluster 23: Choroid plexus - Mixed function	Cluster 36: Non-specific - mRNA processing	Cluster 17: Non-specific - RNA processing	Cluster 52: Non-specific - Cellular respiration	Low tissue specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Cell type enhanced	Detected in many	null	Low immune cell specificity	Detected in all	null	3	0	3	[ "Kidney Renal Clear Cell Carcinoma" ]	[ "Breast Invasive Carcinoma", "Liver Hepatocellular Carcinoma" ]	[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]	69	2
ENSG00000004975	DVL2	Dishevelled segment polarity protein 2	[ "O14641" ]	17	7225342-7234517	Evidence at protein level	Evidence at transcript level	Evidence at protein level	Evidence at protein level	[ "HPA021611", "HPA022914", "HPA064732" ]	[]	[ "Predicted intracellular proteins" ]	[ "Wnt signaling pathway" ]	[ "Developmental protein" ]	[]	[ "Nucleoplasm", "Nuclear bodies" ]	[ "Aggresome" ]	[]	[]	Approved	Approved	null	146	null	null	Cluster 3: Non-specific - Nuclear processes	Cluster 11: White matter - Signal transduction	Cluster 42: Non-specific - Unknown function	Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal	Cluster 64: Non-specific - Transcription	Low tissue specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cell type specificity	Detected in many	null	Low immune cell specificity	Detected in all	null	2	0	2	[ "Kidney Renal Clear Cell Carcinoma" ]	[ "Liver Hepatocellular Carcinoma" ]	[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]	70	4
ENSG00000005001	PRSS22	Serine protease 22	[ "Q9GZN4" ]	16	2852730-2858170	Evidence at protein level	Evidence at transcript level	Evidence at protein level	Evidence at protein level	[ "HPA049161" ]	[ "BSSP-4", "hBSSP-4", "SP001LA" ]	[ "Enzymes", "Predicted secreted proteins" ]	[]	[ "Hydrolase", "Protease", "Serine protease" ]	[]	[]	[]	[ "Secreted in other tissues" ]	[ "Enzyme" ]	null	Approved	null	11	null	null	null	null	Cluster 53: Squamous epithelial cells - Keratinization	Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization	Cluster 81: Squamous epithelium - Keratinization	Tissue enhanced	Detected in many	null	Cancer enhanced	Detected in many	null	Low cancer specificity	Detected in many	null	Cell type enhanced	Detected in many	null	Not detected in immune cells	Not detected	null	1	0	1	[ "Thyroid Carcinoma" ]	[]	[ "Thyroid Carcinoma" ]	71	1
ENSG00000005007	UPF1	UPF1 RNA helicase and ATPase	[ "Q92900" ]	19	18831959-18868230	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA019587", "HPA020857" ]	[ "HUPF1", "KIAA0221", "NORF1", "pNORF1", "RENT1", "smg-2" ]	[ "Enzymes", "Essential proteins", "Plasma proteins", "Predicted intracellular proteins" ]	[ "Host-virus interaction", "Nonsense-mediated mRNA decay" ]	[ "Helicase", "Hydrolase", "RNA-binding" ]	[]	[ "Nucleoplasm" ]	[ "Cytosol" ]	[]	[]	Supported	Approved	null	191	null	null	null	Cluster 27: Non-specific - Mixed function	Cluster 23: Non-specific - Transcription	Cluster 24: Neutrophils - Innate immunity signal integration	Cluster 24: Non-specific - Transcription	Low tissue specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cell type specificity	Detected in many	null	Not detected in immune cells	Not detected	null	2	0	2	[ "Kidney Renal Clear Cell Carcinoma" ]	[ "Skin Cutaneous Melanoma" ]	[ "Kidney Renal Clear Cell Carcinoma", "Skin Cutaneous Melanoma" ]	72	8
ENSG00000005020	SKAP2	Src kinase associated phosphoprotein 2	[ "O75563" ]	7	26667068-26995239	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA005560", "HPA024045" ]	[ "RA70", "SAPS", "SCAP2", "SKAP-HOM", "SKAP55R" ]	[ "Predicted intracellular proteins" ]	[ "B-cell activation" ]	[]	[]	[ "Nucleoplasm" ]	[ "Cytosol" ]	[]	[]	Supported	Enhanced	null	12	null	null	Cluster 2: Dendritic cells - Unknown function	Cluster 22: Non-specific - Mixed function	Cluster 53: Squamous epithelial cells - Keratinization	Cluster 48: Neutrophils - Phagocytosis & degranulation	Cluster 66: Lymphoid tissue - Immune response	Low tissue specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Cell type enhanced	Detected in many	null	Low immune cell specificity	Detected in all	null	4	0	4	[ "Kidney Renal Clear Cell Carcinoma" ]	[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma", "Lung Squamous Cell Carcinoma" ]	[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Squamous Cell Carcinoma" ]	73	1
ENSG00000005022	SLC25A5	Solute carrier family 25 member 5	[ "P05141" ]	X	119468422-119471396	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA046835", "HPA071684" ]	[ "2F1", "ANT2", "T2", "T3" ]	[ "Essential proteins", "FDA approved drug targets", "Metabolic proteins", "Plasma proteins", "Predicted membrane proteins", "Transporters" ]	[ "Antiport", "Chromosome partition", "Host-virus interaction", "Transport" ]	[]	[ "FDA approved drug targets" ]	[ "Mitochondria" ]	[]	[]	[]	Supported	Approved	null	42	null	null	Cluster 33: Non-specific - ATP binding	Cluster 45: Non-specific - Mixed function	Cluster 36: Non-specific - mRNA processing	Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier	Cluster 60: Stomach - Digestion	Low tissue specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Cell type enhanced	Detected in all	null	Low immune cell specificity	Detected in all	null	4	0	4	[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]	[ "Breast Invasive Carcinoma", "Liver Hepatocellular Carcinoma" ]	[ "Breast Invasive Carcinoma", "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]	74	6
ENSG00000005059	MCUB	Mitochondrial calcium uniporter dominant negative subunit beta	[ "Q9NWR8" ]	4	109560209-109688719	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA014058", "HPA048776" ]	[ "CCDC109B", "FLJ20647" ]	[ "Predicted membrane proteins", "Transporters" ]	[ "Calcium transport", "Ion transport", "Transport" ]	[]	[]	[ "Mitochondria" ]	[ "Cytosol" ]	[]	[]	Supported	Enhanced	null	3	null	null	Cluster 33: Non-specific - ATP binding	Cluster 39: Astrocytes - Mixed function	Cluster 46: Lymphoma - Humoral immune response	Cluster 9: T-cells - Adaptive immunity: Regulation	Cluster 51: Lymphoid tissue - Adaptive immune response	Tissue enhanced	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Cell type enhanced	Detected in many	null	Low immune cell specificity	Detected in many	null	2	0	2	[]	[ "Glioblastoma Multiforme", "Lung Squamous Cell Carcinoma" ]	[ "Glioblastoma Multiforme", "Lung Squamous Cell Carcinoma" ]	75	3
ENSG00000005073	HOXA11	Homeobox A11	[ "P31270" ]	7	27181157-27185232	Evidence at protein level	Evidence at protein level	Evidence at transcript level	Evidence at protein level	[ "HPA006770", "HPA035623" ]	[ "HOX1", "HOX1I" ]	[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Transcription factors" ]	[ "Transcription", "Transcription regulation" ]	[ "Developmental protein", "DNA-binding" ]	[ "Cancer-related genes" ]	[ "Nucleoplasm" ]	[]	[]	[]	Supported	Enhanced	null	3	null	null	null	null	Cluster 32: Non-specific - Cell proliferation	Cluster 108: Fibroblasts - ECM organization	Cluster 75: Ovary - Mixed function	Tissue enhanced	Detected in many	null	Low cancer specificity	Detected in many	null	Low cancer specificity	Detected in many	null	Cell type enhanced	Detected in some	null	Not detected in immune cells	Not detected	null	3	0	3	[]	[ "Kidney Chromophobe", "Rectum Adenocarcinoma", "Skin Cutaneous Melanoma" ]	[ "Kidney Chromophobe", "Rectum Adenocarcinoma", "Skin Cutaneous Melanoma" ]	76	4
ENSG00000005075	POLR2J	RNA polymerase II subunit J	[ "P52435" ]	7	102473128-102478922	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA046970" ]	[ "hRPB14", "POLR2J1", "RPB11", "RPB11A", "RPB11m" ]	[ "Metabolic proteins", "Predicted intracellular proteins", "RNA polymerase related proteins" ]	[ "Transcription" ]	[]	[]	[ "Nucleoplasm" ]	[]	[]	[]	Approved	null	null	147	null	null	Cluster 36: Eosinophils - Protein ubiquitination	Cluster 44: Non-specific - Mixed function	Cluster 39: Non-specific - Transcription	Cluster 97: Non-specific - Cellular respiration	Cluster 25: Non-specific - Basic cellular processes	Low tissue specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Cell type enhanced	Detected in many	null	Low immune cell specificity	Detected in all	null	3	2	2	[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]	[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]	[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]	77	4
ENSG00000005100	DHX33	DEAH-box helicase 33	[ "Q9H6R0" ]	17	5440917-5468982	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA071536", "HPA073875" ]	[ "DDX33", "DKFZp762F2011", "FLJ21972" ]	[ "Enzymes", "Essential proteins", "Predicted intracellular proteins" ]	[]	[ "Helicase", "Hydrolase" ]	[]	[ "Nucleoli" ]	[]	[]	[]	Enhanced	Supported	null	12	null	null	Cluster 12: Non-specific - Mitochondrial translation	Cluster 40: Astrocytes - Astrocyte-neuron interactions	Cluster 42: Non-specific - Unknown function	Cluster 17: Non-specific - RNA processing	Cluster 63: Non-specific - Basic cellular processes	Low tissue specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cell type specificity	Detected in many	null	Not detected in immune cells	Not detected	null	0	0	0	[]	[]	[]	78	2
ENSG00000005102	MEOX1	Mesenchyme homeobox 1	[ "P50221" ]	17	43640389-43661922	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA045214", "HPA063788" ]	[ "MOX1" ]	[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Transcription factors" ]	[ "Transcription", "Transcription regulation" ]	[ "Activator", "Developmental protein", "DNA-binding", "Repressor" ]	[]	[ "Nucleoplasm" ]	[ "Cytokinetic bridge", "Cytosol" ]	[]	[]	Approved	Uncertain	null	81	Yes	null	Cluster 9: T-regs - Cell cycle regulation	Cluster 53: Neurons - Mixed function	Cluster 15: Kidney cancer - Membrane components	Cluster 32: Endothelial cells - Angiogenesis & vascular immunity	Cluster 14: Adipose tissue - Angiogenesis	Tissue enhanced	Detected in many	null	Group enriched	Detected in many	6	Cancer enhanced	Detected in many	null	Cell type enriched	Detected in some	9	Immune cell enriched	Detected in some	4	0	0	0	[]	[]	[]	79	1
ENSG00000005108	THSD7A	Thrombospondin type 1 domain containing 7A	[ "Q9UPZ6" ]	7	11370365-11832198	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA000923" ]	[ "KIAA0960" ]	[ "Disease related genes", "Predicted membrane proteins", "Predicted secreted proteins" ]	[ "Angiogenesis", "Differentiation" ]	[]	[]	[]	[]	[ "Secreted to blood" ]	[ "Developmental protein" ]	null	Supported	null	13	null	null	Cluster 46: Basophils - Proteolysis	Cluster 19: Astrocytes - Mixed function	Cluster 17: Neuroblastoma - Neuronal signaling	Cluster 57: Podocytes - Glomerular filtration	Cluster 72: Kidney - Transmembrane transport	Tissue enhanced	Detected in many	null	Cancer enriched	Detected in many	6	Cancer enriched	Detected in many	6	Cell type enhanced	Detected in many	null	Immune cell enriched	Detected in single	53	2	2	1	[ "Kidney Renal Clear Cell Carcinoma" ]	[ "Pancreatic Adenocarcinoma" ]	[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]	80	5
ENSG00000005156	LIG3	DNA ligase 3	[ "P49916" ]	17	34980512-35009743	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA006723", "CAB080348" ]	[ "LIG2", "LIG3alpha" ]	[ "Disease related genes", "Enzymes", "Essential proteins", "Human disease related genes", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins" ]	[ "Cell cycle", "Cell division", "DNA damage", "DNA recombination", "DNA repair", "DNA replication" ]	[ "Ligase" ]	[ "Disease variant", "Primary mitochondrial disease" ]	[ "Nucleoplasm" ]	[]	[]	[]	Supported	Supported	null	48	null	null	Cluster 30: Non-specific - DNA binding	Cluster 16: Non-specific - Transcription	Cluster 27: Breast cancer - Unknown function	Cluster 83: Epicardial mesothelial cells - Basic cellular functions	Cluster 39: Testis - Nuclear processes	Low tissue specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Cell type enhanced	Detected in many	null	Low immune cell specificity	Detected in many	null	4	0	4	[ "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]	[ "Colon Adenocarcinoma", "Skin Cutaneous Melanoma" ]	[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma", "Skin Cutaneous Melanoma" ]	81	5
ENSG00000005175	RPAP3	RNA polymerase II associated protein 3	[ "Q9H6T3" ]	12	47661249-47706030	Evidence at protein level	Evidence at protein level	Evidence at protein level	Evidence at protein level	[ "HPA038311", "HPA038312" ]	[ "FLJ21908", "hSpagh", "spag", "Tah1" ]	[ "Essential proteins", "Predicted intracellular proteins" ]	[]	[]	[]	[ "Cytosol" ]	[ "Primary cilium", "Primary cilium tip", "Basal body", "Acrosome" ]	[]	[]	Enhanced	Enhanced	null	102	null	null	Cluster 14: Non-specific - Unknown function	Cluster 31: Non-specific - Transcription	Cluster 38: Non-specific - Transcription	Cluster 17: Non-specific - RNA processing	Cluster 63: Non-specific - Basic cellular processes	Low tissue specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Low cell type specificity	Detected in many	null	Low immune cell specificity	Detected in all	null	3	0	3	[ "Kidney Renal Clear Cell Carcinoma" ]	[ "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]	[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]	82	6
ENSG00000005187	ACSM3	Acyl-CoA synthetase medium chain family member 3	[ "Q53FZ2" ]	16	20610243-20797581	Evidence at protein level	Evidence at transcript level	Evidence at protein level	Evidence at protein level	[ "HPA041013" ]	[ "SA", "SAH" ]	[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]	[ "Fatty acid metabolism", "Lipid metabolism" ]	[ "Ligase" ]	[]	[]	[]	[]	[]	null	Uncertain	null	3	null	null	Cluster 36: Eosinophils - Protein ubiquitination	Cluster 6: Non-specific - Immune response	Cluster 47: Leukemia - Hemostasis	Cluster 94: Gonadal somatic cells - Mixed function	Cluster 16: Liver & Kidney - Metabolism	Tissue enhanced	Detected in many	null	Cancer enhanced	Detected in many	null	Low cancer specificity	Detected in many	null	Cell type enhanced	Detected in many	null	Immune cell enhanced	Detected in many	null	1	0	1	[ "Kidney Renal Clear Cell Carcinoma" ]	[]	[ "Kidney Renal Clear Cell Carcinoma" ]	83	7
ENSG00000005189	REXO5	RNA exonuclease 5	[ "Q96IC2" ]	16	20806429-20849665	Evidence at protein level	Evidence at protein level	Evidence at transcript level	Evidence at protein level	[ "HPA040755", "HPA040868", "HPA066145" ]	[ "NEF-sp" ]	[ "Predicted intracellular proteins" ]	[]	[ "Exonuclease", "Hydrolase", "Nuclease", "RNA-binding" ]	[]	[ "Nuclear membrane" ]	[ "Nucleoli", "Endoplasmic reticulum" ]	[]	[]	Approved	Approved	null	2	null	null	Cluster 46: Basophils - Proteolysis	Cluster 4: Non-specific - mRNA splicing & Cell cycle	Cluster 47: Leukemia - Hemostasis	Cluster 53: Late primary spermatocytes - Meiotic division & transition	Cluster 57: Testis - Spermatogenesis	Tissue enriched	Detected in many	9	Low cancer specificity	Detected in all	null	Low cancer specificity	Detected in all	null	Cell type enhanced	Detected in many	null	Immune cell enriched	Detected in some	15	1	0	1	[ "Glioblastoma Multiforme" ]	[]	[ "Glioblastoma Multiforme" ]	84	5

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Human Protein Atlas Gene Annotations

This dataset contains a viewer-friendly gene-level Parquet table derived from the Human Protein Atlas JSONL source in this repository. Each row is one gene/protein entry. Repeated cancer-prognostic and RNA expression measurements are available as metadata tables.

Splits

The split is deterministic by Ensembl ID: sha256(ensembl_id) % 10. Bucket 0 is test; buckets 1 through 9 are train.

Split	Rows
train	18,138
test	2,024
total	20,162

Dataset Statistics

Field	Value
Gene rows	20,162
Cancer prognostic metadata rows	442,504
RNA expression measurement rows	149,150

Usage

pip install datasets

Load all splits:

from datasets import load_dataset

ds = load_dataset("LiteFold/HumanProteinAtlas")
print(ds)
print(ds["train"][0]["gene"])

Load one split:

from datasets import load_dataset

train = load_dataset("LiteFold/HumanProteinAtlas", split="train")

Filter genes with protein-level evidence:

from datasets import load_dataset

ds = load_dataset("LiteFold/HumanProteinAtlas", split="train")
protein_level = ds.filter(lambda row: row["evidence"] == "Evidence at protein level")
print(protein_level[0])

Load metadata tables directly:

import pandas as pd
from huggingface_hub import hf_hub_download

prognostics_path = hf_hub_download(
    repo_id="LiteFold/HumanProteinAtlas",
    repo_type="dataset",
    filename="metadata/cancer_prognostics.parquet",
)
prognostics = pd.read_parquet(prognostics_path)
print(prognostics.head())

expression_path = hf_hub_download(
    repo_id="LiteFold/HumanProteinAtlas",
    repo_type="dataset",
    filename="metadata/rna_expression_measurements.parquet",
)
expression = pd.read_parquet(expression_path)
print(expression.head())

Key Columns

Column	Description
`ensembl_id`	Ensembl gene ID.
`gene`	Gene symbol.
`gene_description`	Gene/protein description.
`uniprot`	UniProt accession, when available.
`chromosome`	Chromosome.
`position`	Genomic position string.
`evidence`	Main HPA evidence level.
`hpa_evidence`	HPA-specific evidence level.
`uniprot_evidence`	UniProt evidence level.
`nextprot_evidence`	neXtProt evidence level.
`antibodies`	HPA antibody IDs.
`gene_synonyms`	Gene synonyms.
`protein_classes`	Protein class labels.
`biological_processes`	Biological process annotations.
`molecular_functions`	Molecular function annotations.
`disease_involvement`	Disease involvement labels.
`subcellular_main_locations`	Main subcellular locations.
`subcellular_additional_locations`	Additional subcellular locations.
`secretome_locations`	Secretome location annotations.
`secretome_functions`	Secretome function annotations.
`rna_tissue_specificity`	RNA tissue specificity category.
`rna_tissue_distribution`	RNA tissue distribution category.
`prognostic_cancer_count`	Number of cancers where the gene is prognostic.
`validated_prognostic_cancer_count`	Number of validated prognostic cancer entries.
`potential_prognostic_cancer_count`	Number of potential prognostic cancer entries.
`prognostic_cancers`	Cancer names with prognostic entries.
`split_bucket`	Deterministic split bucket from `sha256(ensembl_id) % 10`.

Preparation

The normalization script used to create the Parquet files is included at scripts/prepare_hpa_dataset.py.

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